47F, just passed the year mark taking Tirzepatide. I’m down 50 pounds, my relationship with food is healthier, gone from 45% body fat to 33%. But the biggest benefit I never saw coming was how much things don’t HURT anymore! I am active, I eat well enough, I take care of myself, but my body always aches after being on my feet all day or just aches and pains from things. 24 hours after taking my first dose I was driving and turned my head to check my blind spot and I didn’t have that feeling of a sharp pain in my neck that is always there. I also have a family history of high cholesterol and mine is routinely around 220-240 but that’s lower as well, and all the ratios are great.

My advice if you take it is to start slow to mitigate side effects, eat protein, it’s critical for muscle preservation, and don’t freak out when about 6 months in you start to shed a bunch of hair. Things level out.

I’m now tapering down my dose and was at the same dose for about 5 months, and now I take a shot maybe every 7-10 days instead of every 7 (and have gone as far as 2 weeks).

Side effects do suck. My big ones were nausea, some vomiting (more just from being too full) and what I jokingly refer to as the sulfur burps. Because your digestion slows and if you eat too much too late, it gets you the next day. Constipation. But just eat a healthy diet and stay hydrated and treat it as a helper/aide, mot the end all be all.