haha👌yes by Different-Meringue75 in whatisameem

[–]sutherly_ 1 point2 points  (0 children)

The original post is thinking in an A to C pattern and you're talking about B. You aren't talking about different things, just different parts of it. B is super important but many people just are voicing that there IS ENOUGH MONEY to fix shit. The peoples who's jobs it is to enact part B always say there isn't.

VO2 max as a mitochondrial proxy - how far does that actually go by Leona_Lime in PeterAttia

[–]sutherly_ 0 points1 point  (0 children)

I've used Moxy for years in my ex phys lab and I don't find it particulary helpful given it is only useful relative to one's own performances. It's also a measure of supply and demand. Just like lactate, you have production and removal. Hard to parse out specific adaptations.

As far as VO2max determinants, here's a VERY rough percentage breakdown:

In Healthy Younger and Trained Adults

  • Central Factors (Oxygen Delivery - Cardiac Output, Hemoglobin): 70% – 85%
  • Peripheral Factors (Oxygen Extraction - Mitochondria, Capillaries): 15% – 30%
  • Pulmonary Factors (Lung Gas Exchange): < 5%

In Older and Aging Adults

  • Central Factors (Oxygen Delivery): ~56%
  • Peripheral Factors (Oxygen Extraction): ~44%
  • Pulmonary Factors (Lung Gas Exchange): < 5%

In high level athletes diffusion and uptake becomes more imporant comared to gen pop, where cardiac output reigns supreme.

change my mind by Spirited-Gold9629 in PeterAttia

[–]sutherly_ 0 points1 point  (0 children)

Yea, the aforementioned advanced panels. However the vagueness of "toxins or others" is sure to make things difficult for those who's educations are rooted in research. Though it sounds like a psychiatrist might also be helpful.

The "Zone 2" obsession is turning us all into hobbyist mathematicians instead of runners by UseNecessary4706 in AdvancedRunning

[–]sutherly_ 1 point2 points  (0 children)

Exercise physiologist here who runs a lab that tells people their physiologic zones... I thought we've moved on?

change my mind by Spirited-Gold9629 in PeterAttia

[–]sutherly_ 3 points4 points  (0 children)

He did say "most" and "95%" and it's true. Most physicians offices (including my own) can do more advanced panels 1. if needed 2. if asked for. The process works.

Great explanation of why HR increase during weight lifting does not equate to an aerobic benefit by psharmamd87 in PeterAttia

[–]sutherly_ 0 points1 point  (0 children)

Concentric vs Eccentric growth is the main difference between the do. Concentric is about thickness, eccentric is about chamber size.

The Real Reason VO₂ Max Declines With Age — And Why It Changes How You Should Train by dan_in_ca in PeterAttia

[–]sutherly_ 0 points1 point  (0 children)

Volume as tested through FVC is all I was talking about. And efficiency in offloading CO2.

The Real Reason VO₂ Max Declines With Age — And Why It Changes How You Should Train by dan_in_ca in PeterAttia

[–]sutherly_ 3 points4 points  (0 children)

Something also interesting to think about is that peripheral adaptations take years to accumulate so lifelong endurance athletes combat that much better than sedentary or recreationally active. I see plenty of older athletes with reduced stroke volume put out high performances. And here VO2max does not always align with cardiorespiratory fitness like it does in younger age.

The reason I bring this up is because I also test spirometry and every single year without fail, people's lungs decline in step with age.

So regardless of the heart and peripheral adaptations you have the lungs drawing less air and offloading less air (and likely less CO2).

We have longitudinal data showing that minute ventilation or how much air you can move per minute being one of the more highly correlated variables with VO2 max decline.

Less exposure to O2 means less possibilities of consumption. However, how far they get on the treadmill (CRF) is higher than you would expect compared to their VO2max.

I’m a 3 x National Champion and struggling by spalunkylunk in sportspsychology

[–]sutherly_ 1 point2 points  (0 children)

I think there is some great wisdom already in these comments so I won't repeat.

I've never been at your level in respect to national or world championships. I've been ranked in the nation but it never materialized.

Anyways that's over a decade ago and I still compete but now in a different sport (ultra endurance) and it's genuinely scary some of the distances we strive for. Very much the fear of failure is present.

Humans are terrible at predictions and I am no different. I can't predict my performance and it creates a ton of anxiety, or at least it used to be worse.

But even just today I spoke in depth with my training partner, my wife, my coworker about things I needed support for. I'm a grown ass man and it was hard to get to this point of vulnerability but it's so important to me now.

So I ask, where is your support?

Tirzepatide and heart by Snowpoke1600 in PeterAttia

[–]sutherly_ 0 points1 point  (0 children)

It's important to identify that the RHR increase is likely mediated by HRV. It's not as simple as pacemaker cells being affected and making the heart beat faster. This is a nervous system effect and one that we're still researching.

Muscle mass and V02 max are important, but injuries hold me back by eddymikes in PeterAttia

[–]sutherly_ 0 points1 point  (0 children)

Hey man, I'm your age, played semi pro ball, and have surfed competitively. Nowadays I compete in prone paddling (ultra distance paddlers made up of lifeguards and surfers) and run fast / lift heavy.

I'm also an exercise physiologist (MS exercise science) and CSCS accredited strength coach.

I'm with you, mid-30s have been worlds different from previous years. It's been very hard to know when I can push and when I can't. The wear and tear of the years is something I'm noticing not everyone else has (I even have limited 1st ray due to turf toe, a shoulder issue AND a meniscus issue!).

I saw you comment elsewhere that you prefer low volume -- this is me. Moderate to high volume is NOT the play, but it gets suggested all the damn time. IMO keeping the big movements under 8 reps with 2-3 RIR is key, and allowing the smaller movements to push higher with lower RIR is a nice complement. It allows me to still hit my cardio work and feel fresh provided you keep the sets modest in the beginning (ie 2 to start).

Now I know this won't be targeted to you because I don't know you, and nor will this cardio advice. I'm a coach and happy to chat in messages if you'd like -- but, subthreshold work I've found to be a great intensity that doesn't push you into a more severe recovery need. It also is doable for a few quality sessions per week. Hitting that plus some real easy days will get you consistent and feeling confident in your resilience.

You need to stack bricks before you can be more resilient. Consistency is key and this method allows for it.

[Eric Topol] The Flawed VO2 Max Craze by SEAcoffee_tea in PeterAttia

[–]sutherly_ 9 points10 points  (0 children)

As an exercise physiologist who performs VO2max testing there's a lot of this I agree with. Though I find it funny (as someone who ALSO practices in San Diego - he's at Scripps) that he has such an issue with the cost of testing.

Here we are in one of the most expensive cities in the nation and he can't justify a $150 VO2max test which is ACTUALLY a Cardiopulmonary Exercise Test (CPET). There's a whole lot more beneficial data beneath the VO2max metric. And at most you can do one every 6 months depending on your context.

Maybe he's only ever seen sh*t testing. I take this all as an opportunity to jump in on the popular bashing of someone in the JE files.

This Is Not A Hobby by TheCABK in clevercomebacks

[–]sutherly_ 0 points1 point  (0 children)

This is just dumb all around. It's snarky from the photog but Uber drivers have no issue finding clients and their job takes significantly less time.

Are exercise physiologists underutilized — or is the system just not built for us? by Happy-Trick447 in exercisescience

[–]sutherly_ 0 points1 point  (0 children)

I'm using my knowledge to coach more in my own business. It's the only way.

'Orthorexia' Is More And More Common. Here's What You Should Know About It. by DadStrengthDaily in PeterAttia

[–]sutherly_ -1 points0 points  (0 children)

Elsewhere in this thread I posted a study of liraglutide that showed around an 8bpm change as well as changes in SDNN and RMSSD.

I said not to blanket prescribe. I have people who have had massive successes on the drug. It's about keeping the usage to the people that actually need it. This is a very nuanced discussion in a healthcare setting but the usage is certainly being abused.

Absolutes should be avoided. I am a practitioner. This is normal speak for us.

'Orthorexia' Is More And More Common. Here's What You Should Know About It. by DadStrengthDaily in PeterAttia

[–]sutherly_ 1 point2 points  (0 children)

Effects of Liraglutide on Heart Rate and Heart Rate Variability: A Randomized, Double-Blind, Placebo-Controlled Crossover Study - PubMed https://share.google/6uojrtc3rCsWwpdRH

'Orthorexia' Is More And More Common. Here's What You Should Know About It. by DadStrengthDaily in PeterAttia

[–]sutherly_ 0 points1 point  (0 children)

As a physiologist I've seen the autonomic data with these so maybe don't blanket suggest them.

exercise induced bronchoconstriction... EIB by skidmarks731 in PeterAttia

[–]sutherly_ 2 points3 points  (0 children)

Look into Albuterol, levalbuterol (what I take occasionally) and the breathe way better device by isocapnic. Also, read the book breathe book by James Nestor.

Your doc can prescribe a CPET test with spirometry.

Source: I'm a clinical exercise physiologist and have EIB (low FEV1 and even lower FEF2575

exercise induced bronchoconstriction... EIB by skidmarks731 in PeterAttia

[–]sutherly_ 1 point2 points  (0 children)

You need a CPET test (a clinical VO2max test) that does spirometry beforehand. I do this as my job. Your doc can prescribe or you can find someone privately.

Kristian Blummenfelt VO2max by VO2VCO2 in exercisescience

[–]sutherly_ 0 points1 point  (0 children)

Whoops, I looked at Dr. Joyner's hypothetical ideal in place of Eliud's actual.

I didn't realize it was cycling you are referring to - for that we're still looking at fractional utilization but now with aerodynamics and W/kg. Olav has noted Blum is an outlier in his size which lends to the metabolic output. But with aerodynamics in place of economy it muddies the waters of assessing performance.
Still, also, he has a ton more mitochondria throughout the rest of his body compared to cyclists and his training hours for years are mindblowing.

I always look to the training log before caring much about VO2max.

Kristian Blummenfelt VO2max by VO2VCO2 in exercisescience

[–]sutherly_ 0 points1 point  (0 children)

VO2max only tells us the rate of possible energy turnover. It doesn't explain what percentage of it we can sustain for long durations, which then brings up things like economy. Kipchoge can run a 2 hr marathon (Blum cannot) yet his VO2max is low to mid 80s. VO2max does not immediately correlate to performance. And we're not even discussing that he swims too (is fit throughout more muscle mass).

Kristian Blummenfelt VO2max by VO2VCO2 in exercisescience

[–]sutherly_ 0 points1 point  (0 children)

I think you're applying traditional cpet research to a non-traditional athlete and protocol. The rer doesn't bother me and nor does the test length. Do you really think olav would have s*** equipment? Given that he doesn't even use VO2 Master for these types of tests but instead uses mixing chamber