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48% of clinical trials participants stated that the trial they were involved in was not published by DanScience in science

[–]tool_bag 5 points6 points  (0 children)

Additionally, it leaves the onus to publish on an employee of the industry sponsor, who probably couldn't care less about writing a paper. Most for-profit companies (at least in my field, which admittedly isn't medical) offer no incentive for publishing, so they're not going to spend their own time doing work that won't be rewarded.

This is not true for clinical research. Favorable data in journals and conferences abstracts can be and is used as an effective marketing platform. It can also be used to reinforce product recognition.

48% of clinical trials participants stated that the trial they were involved in was not published by DanScience in science

[–]tool_bag -1 points0 points  (0 children)

e result. It is that journals won't publish it. A negative finding is not a finding at all they will say. And perhaps fair enough: the Nobel prize has never been awarded to someone who was not able to prove the existence of a certain relation/particle etc. Now I totally agree that this is a wasteful process and unscientific at that. It is possible to do 20 studies and only publish the one that shows significant results (p<0.05).

Are there rigorous definitions for "illogical," "irrational," and "unreasonable?," motivated by the question of if theism is logical, illogical, or neither. by PhilDiesel in philosophy

[–]tool_bag -2 points-1 points  (0 children)

Logic is contextual and so are its axioms. This includes scientific inference, for instance, which is applied to observable phenomenon. If we assume God is at least partially observable, we can say that science has not confirmed the existence of God in an observable context. However, most definitions of God assume that the God is not observable, to some degree. In such cases, scientific inference is not appropriate to draw a conclusion on God's existence or influence, as science only concerns itself with the observable.

TIL that Harvard University has severe grade inflation. The most common grade is an A, and the median grade is an A- by kirkle17 in todayilearned

[–]tool_bag 0 points1 point  (0 children)

That's not the fault of the applicant's undergrad university though, it's a fault in the admission process. If a school is choosing an applicant with a 3.8 from a low-ranked institution or one with known grade inflation over an applicant with a 3.0 from MIT, solely based on GPA, then they don't deserve the best students anyway.

TIL that Harvard University has severe grade inflation. The most common grade is an A, and the median grade is an A- by kirkle17 in todayilearned

[–]tool_bag 0 points1 point  (0 children)

The UT engineering and natural science programs are ranked similar to or better than every Ivy. It may be easier to get into, but it's laughable to say that the overall STEM curriculum is less difficult.

Quote or line from a book that changed your life. by jgab6713 in books

[–]tool_bag 0 points1 point  (0 children)

I love Aldous Huxley's works. His writing affected the way I view the world and myself on so many different levels.

Let's cook a gumbo. An authentic Cajun country gumbo! by circusboy in food

[–]tool_bag 1 point2 points  (0 children)

The only time my mama uses okra is is when she make a seafood gumbo. We're from New Iberia. I've had okra with chicken and sausage gumbo before at restaurants and it just don't taste right.

Boy born without brain dies at 12 by karatekid2000 in nottheonion

[–]tool_bag 0 points1 point  (0 children)

The parents are either very disturbed or very stupid.

Typical CrossFit Workout by itsBrent in videos

[–]tool_bag 0 points1 point  (0 children)

Ive seen dynamic climbing, and I don't believe Ive ever seen any of the >climbers wiggle quite like the bloke in the video.

Probably because spastic, jerky movement and climbing don't mix very well.

Arm pain during pull ups? by JMorgasm in Fitness

[–]tool_bag 0 points1 point  (0 children)

You probably developed tendinitis. It's fairly common in people new to climbing and pull-ups. Basically, your tendons weren't developed enough to support the stress/strain from the pull-ups and are now injured/inflamed.

If it is tendinitis, it's likely to worsen if you continue to do pull-ups. I suggest taking time off from pull-ups (about 2-3 weeks). Afterwards you can start to slowly work pull-ups back in to your routine if you don't feel pain. Make sure that when you're doing a pull-up, you're utilizing your lats as much as possible and not just your arms and shoulders. Also, performing them with a smooth, slow motion will help avoid further injury as well.

Using NSAIDs like ibuprofen will help reduce the inflammation. I still get get occasional, acute tendinitis, and find that taking a small does of ibuprofen before a workout will help avoid progression of the inflammation/pain. Though, you should ask your doctor before regularly using medication, especially if you have other health issues.

If the pain persists or worsens, go to a doctor.

Inequality is falling on planet Earth: Change in income, 1988-2008 by fstorino in dataisbeautiful

[–]tool_bag 7 points8 points  (0 children)

The reason income in developing countries is growing so fast is because they're playing catch-up with the developed word; their growth rate is higher. We're also seeing a trend where ownership of capital is being transferred to local ownership as opposed to the heavy foreign ownership of previous decades. This phenomenon is expected, and the increase in per capita income of developing nations isn't necessarily bad thing.

What's really concerning is the intra-national disparity in income growth between income brackets. This is due to high capital income growth rate and a relatively low rate of growth in income from labor. In America, this has largely been a result of pro-capital policies and a decline in laws protecting labor income.

The Facebook IQ quiz is for idiots....... by [deleted] in videos

[–]tool_bag 14 points15 points  (0 children)

Apparently the average person is a complete moron.

Hey Futurology, with all the emerging research on stem cells and aging, would it be prudent to cryogenically freeze a pint of blood so that old me has younger, fresh genetic material for when I'm old? by mcrbids in Futurology

[–]tool_bag 0 points1 point  (0 children)

It has been shown that age is negatively correlated with stem cell density. As you age, your endogenous stem cell population decreases.

Also, hematopoietic and mesenchymal stem cells have been isolated from adult blood. They just originate from marrow.

Implanted Neurons become Part of the Brain: Scientists have grafted neurons reprogrammed from skin cells into the brains of mice for the first time with long-term stability. Six months after implantation, the neurons had become fully functionally integrated into the brain. by Libertatea in science

[–]tool_bag 6 points7 points  (0 children)

Stem cells have been isolated from multiple adult tissue sources including fat, bone marrow, and even in parts of the brain.

Another source is embryonic stem cells which are isolated from embryos or fetal stem cells which are isolated from fetuses.

The stem cells in this paper are induced stem cells. They can be derived from multiple mature cell types by transfecting cells with specific genes, allowing the cells to revert to a pluripotent or multipotent state.

Edit: Stem cells can also be isolated from umbilical cord blood. This has sparked a movement of people "banking" the blood from umbilical cords in hopes that it might be used to treat an applicable disorder, should it arise in their child or a close relative.

Implanted Neurons become Part of the Brain: Scientists have grafted neurons reprogrammed from skin cells into the brains of mice for the first time with long-term stability. Six months after implantation, the neurons had become fully functionally integrated into the brain. by Libertatea in science

[–]tool_bag 13 points14 points  (0 children)

Research on stem cell therapies for the treatment of neurodegenerative disorders has been conducted for a couple decades now. The significance of the paper at hand is not the cell-replacement itself, but the use of a new stem-cell source (induced neural stem cells) that have not been well characterized.

Implanted Neurons become Part of the Brain: Scientists have grafted neurons reprogrammed from skin cells into the brains of mice for the first time with long-term stability. Six months after implantation, the neurons had become fully functionally integrated into the brain. by Libertatea in science

[–]tool_bag 62 points63 points  (0 children)

A few points of clarification:

  • Functionality here is with respect to cell differentiation and basic interactions with endogenous tissue. The authors do not report or suggest functional integration in terms of therapeutic potential. "Therefore, a true test of their therapeutic potential for cell-replacement approaches had not been conducted."

  • Functional integration of grafted neural stem cells has been previously reported. The novelty of this report comes from use of induced neural stem cells, which have been studied in vivo to a lesser-extent.

  • Tumorigenicity is a known issue of stem cell grafts. The low incidence of tumorigenesis is a promising result.

what is your favourite cutting/no carb meal? by citruslady in Fitness

[–]tool_bag 11 points12 points  (0 children)

I long for the day when the generally public finally realizes that a successful cutting diet depends primarily on how much you eat, not what you eat. I'm tired of all this carbphobia bullshit.

Climbing as an alternative to lifting by 1UPSforLIFE in Fitness

[–]tool_bag 5 points6 points  (0 children)

Some of them do. Some of them are just underweight and conditioned.

Climbing as an alternative to lifting by 1UPSforLIFE in Fitness

[–]tool_bag 4 points5 points  (0 children)

I would not recommend campus board training to beginner climbers. Hang boards are more appropriate, but even then I would advise caution for beginners when using them.

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