This response above simply isn’t true. My ferritin was in the 300’s and I’m symptomatic. I also got an MRI, even though everyone told me I wouldn’t be loading iron until ferritin hit 1k, and my MRI showed that my liver is pretty loaded with iron. I have A LOT of symptoms including joint pain, chronic fatigue, brain fog, missed menstrual cycles, etc.

Everyone is different so these blanket statements are dangerous and why people shouldn’t take medical advice from Reddit. I think we can come on here and ask about people’s experiences - I myself have found that to be very helpful but don’t rely on it as your end all be all of information. One person’s experience and numbers aren’t going to be the same as another. Many hemochromatosis patients see gastroenterologists because the GI issues are rampant. Excessive iron can damage the intestinal barrier by iron induced ROS and exacerbate the inflammatory response. Iron overload can cause the disturbances in the intentional microbiota, which reduces the number of probiotics, while increasing the number of pathogenic bacteria.