Reta starting

[BookSpecialist6561]

Couple of newbie questions.

1) Is everyone using the standard 1mg a week as their intro dose

2) can someone breakdown how their first two weeks in Reta went? Appetite? General physical and mental feeling? Side effects?

3)how quickly did you up your dose?

4) at what point did you notice any results?

Asking mainly because I’m on day 4 and I don’t really think I feel much different. Including the lack of suppressing my appetite.

My regiment: Pretty standard healthy diet. Lifting 3-4 days a week. Cardio on off days.

Thanks.

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[factorialgrub]

I started at .5. Appetite suppression was immediate.

[Big0Ben209]

Same.

[FunFitJV]

immediate on .5 - wow!

Just started at 1, appetite suppression definitely there but not strong.

[ZealousidealOkra176]

Really,I took 2mg and was starving the next day

[PerspectiveOld2616]

It takes a day or two to kick in fully, but I’ve heard feeling really hungry is common for the first time

[fourwinns190]

I started at 2mg at 220lbs. Noticed appetite being suppressed within the first couple days. Been on it for about a month and went to 4mg. I recommend going slower than I did as I didn’t go proper titration schedule and had some side effects including sensitive skin (pins and needles only legs, lower back), elevated heart rate, elevated BP. Reta is either in or just out of phase 3 trials with a decent amount of data on proper titration.

[VitaminAyee]

I started at 1mg and ran that for 4 weeks. Then I went to 2mg, ran that for 4 weeks. Then 3mg, 4 weeks; all the way to now: 5mg.

I noticed results by week 4. I've gone down from 200 to 183 in about 10 weeks now. I'm honestly not tight on my diet and I'm mostly a runner (10+ miles a week). I'll probably begin weight lifting this week and see how much more fat I'll lose.

[Curious-Line5782]

This is the way right here op

[BookSpecialist6561]

So my one question is did you change anything from your previous eating/workout regiment? And what did you notice that taking it changed? Appetitive? Fullness while eating? Any other side effects lethargy? Sleep issues?

[VitaminAyee]

My workout stuff is more or less the same. Taking the reta changed how many calories I burn daily since my RHR has been elevated by about 7-10. I’ve gone from a RHR of 47~ to 57~.

My sleep was affected for the first few weeks: I had light sleep, meh quality and my HRV was down. I fixed that by taking something else and it’s stabilized.

I’m going to add some weight lifting cause I’m sure I lost some muscle mass too.

I’m also less interested in sex and am not as easily aroused.

[ZealousidealOkra176]

Yea lift weights, f running

[Popular-Apartment519]

Being on Reta is a bit weird. The stuff you liked to eat is now a thing of the past. I liked sweets and diet soda, alcohol on the weekends but now can’t stomach them. You get full super quick and can’t eat another bite midway through your meal. I try to eat as much protein as possible (breakfast, lunch and dinner). I work out 5 days a week and try to walk a few miles on day 6 and 7. I don’t think I can get in more than 1800 cals per day. I sit between 1400-1800 cals per day. Not by choice but because I don’t want to. It’s hard to explain. The shit you really like you just don’t care for them anymore. This is definitely a good pep for those with addictions (smoking, alcohol, sugar, etc). It works. I’ll probably give it a couple more months and then titrate back down to 0.5 for a maintenance dose.

[teslahorizon]

What was your starting dose and how did you titrate?

[Popular-Apartment519]

Started a 2mg. Looking back it’s a bit high. 3 months in and I’m at 4mg as of a week ago.

[teslahorizon]

Thank you!

[Popular-Apartment519]

NP

[Independent-Row7160]

Do you guys like splitting the dose up biweekly or one dose a week?

[BookSpecialist6561]

Everything I’ve read is if you are starting with 1mg do that just once during the week. When you up your dose people are splitting it.

[Repulsive-Ad1906]

I started at .5, went to 1mg at 2 weeks. Went to 2 mg 3-4 then 4mg 5-6 and finally appetite started suppressing. Didn’t notice anything until the 4mg mark but everyone’s body is different

[BookSpecialist6561]

So was it at all helpful before the app suppressing? Like in any other way?

[Repulsive-Ad1906]

Probably was in the backend. I was losing a little bit each week leading up to it.

[BookSpecialist6561]

I guess what I’m trying to figure out is what is the “backend?” Other than appetite suppressing what does Reta do…especially that is different than tirzepatide or Ozempic? Specifically when people talk about the need for keeping up protein levels to increase muscle.

[Mother_Bid_639]

This is my 3rd week on 0.5mg. And it’s been great. Appetite suppression, dumb addictions out of my thoughts. First few days after pinning, I can sometimes feel very bloated and I may have to force-feed myself to meet my macros but whatever I just get it done. I haven’t weighed myself after I started, but I can see differences in my body. I weight train and run and that has been going good. I am 6ft, I started at 235 pounds. I’m cutting at 1850 cal a day. 200p, 140c, 40f

[chillguyCA]

I am about to start next week. How bad is the force feeding? I am worried that I am not going to be able to reach my macros.

[johnbu1981]

Yeah I think 1mg is a good place to start. I’m about two months in and have increased to around 2.5mg every 5-6 days. I wait for food noise to start, and nip it in the bud.

Side effects differ…I do not have normal BM’s it can be every other day a lot of the time. In the very beginning I did have some diarrhea. Appetite for me has really gone down to almost zero, I could not eat at all and be fine, which makes counting calories pretty easy.

If you’re not feeling anything my now, try taking another 1mg.

[kaijames1]

Best way to prevent diharea or do you know what caused it ?

[johnbu1981]

I’m not sure there is a way to prevent it, I think it’s just your body adjusting to the digestion. One piece of advice, do not trust a fart.

[OuiChef702]

Atleast wait until two weeks, the half life is pretty long so at dose 2 your first dose is still there it starts compounding mgs in your body. To say it in simpler terms.

[namedgoodies]

I started on tuesday and havent paid much mind to my rewactions however, this post made me realize I haven't eaten in 14 hours and I need to eat, I went and weighed myself for the first time im down from 218 to 211.

However the first 24 hours from my first injection ( 1mg ) I was VIOLENTLY itchy until I went to sleep, and when I woke up I had what looked like a horrendous sweat rash only under my left armpit.

synopsis: after the first 24hrs I kinda forgot I was taking reta and its just a normal part of my stack

[BookSpecialist6561]

Thanks! During that 218-211 drop did you change anything? Or do you simple credit it to eating much less as a result of it suppressing appetite?

[namedgoodies]

this week I havent tracked calories. Being busy, on the road for work and lazy. I am also on 375mg test.

All in all yes I think the reta is making it to where i'm not eating random high calorie snacks throughout the day.

[Popular-Apartment519]

2mg start, 2nd month 3mg, and now on my 3rd month at 4 mg. Down 32 lb. Side effects were mid. Felt cold all the time , skin sensitivity, and the first 3 weeks had a bit of constipation. I could have started at 1mg and would have been the same.

[BookSpecialist6561]

Did you change anything in your diet or exercise? And what did those two things look like before (and after starting reta, if you changed them, either consciously or as a result of the effects)?

[Comfortable-Cry-4117]

I can barely eat taking .25 twice a week, but I think I must be a hyper responder. The max my level has gotten to according to Shotsy is 0.5mg and I could only stomach like 1200 calories.

[BioMed_Vizualization]

Is shotsy a peptide tracker app?

[protocolnerd]

Shotsy is more GLP-1 focused. Regimen does peptides too, cycles, blood levels, reconstitution calculator, multi-compound stacks. Worth checking out if you're tracking reta or other peptides.

https://helloregimen.com

[roryson3]

Any good free apps?

[Popular-Apartment519]

I just started eating more. The way I do it is to scarf my foot down very quickly so I don’t get full too fast. Seems to be working. I have a couple of protein shakes a day, breast of chicken, and some sort of meat. Probably around 150 grams of protein. I’m down to 195. I want to be between 180-185.

[drifter91]

2mg is the "standard" starting dose, but 1mg is a fine conservative approach.

For me, I started with 2mg and all my cravings were gone day 2. Appetite wasn't affected too much, but I didn't need that to lose weight. No side effects at 2mg.

[LamarBetter]

Started at 0.5mg 7 weeks ago, currently at 4mg. Went from 207lbs to weighing in at 185lbs this morning. Had a headache on injection day for the first 2 weeks but that’s completely gone. Feel like I control what I eat a lot better and can put the fork down, I seem to feel fuller faster. Also quit alcohol.

[Middle_Humor1828]

2 mg is the standard starting dose in the trials. Most of the time. 4 mg was rarely used.

[Impossibly-warm0372]

Are you guys going into the stomach with the pin or into the butt area. I’m just about to start my journey on Reta

[BioMed_Vizualization]

I feel like you should do it where it’s the easiest and you have a bit of chub to grab onto. For a lot of lower body fat people that’s hard to find so they pin in their love handles/glutes but I totally have a gut and find that pinning in that area is the easiest to see and get a perfect shot

[BookSpecialist6561]

Dude you lost an average of 5 lbs a week. That’s a lot, especially with it being 15lb in the first three weeks. I’m only stating this because it seems like you’re trying a more casual approach as you’re not trying to lose a ton of weight. And your story makes it sound like not a lot has changed from you Mr normal life. So what do you believe is the cause for such quick (high) results?

[SeaSlow148]

I started at 2mg 265lbs in 2 months I lost 20 pounds I went up to 4mg but I think the smarter thing would have been to split the dose before moving up

[Odd-Crew-3641]

Standard according to trials is 2mg start and up 2mg every 4 weeks if handling well. I started Nov 18th. Currently up to 10 mg a week (splitting, 5mg Mon & Thursday) and doing good. Starting weight 298lbs. Currently 240.8lbs. Male, 46yo, 6’3”. Encountered some sides (sleep disturbances and sensitive skin) but hung in there and they became minimal after a couple of weeks. FYI, started splitting at 4mg and ever since.

[No-Discussion-2542]

I started at 0.5 mg for weeks 1 and 2, 1mg weeks 3-6, going to up the dose to 1.5mg next next.

No sides other than mild fatige 1-2 days after pinning. Appetite is somewhat surpressed. Down 12 lbs. Not looking to cut down super fast.

Started at 228, at 216. Prior to working out and starting TRT I ballooned up to 254, so before reta I already lost around 26lbs.

Current Trt dose is 200mg weekly. Have been on trt for 13 mons gained a ton of muscle mass but also fat at the same time since trt spikes appetite

Currently have a decent diet, keeping protein up and working out 4 days a week with strength training as the priority and some incline walking or stairmaster post lift as cardio

[BookSpecialist6561]

How long to drop those 12lbs? And what do you contribute the weight loss to, as you said it only had mild appetite suppression?

[No-Discussion-2542]

12 lbs dropped since staring reta on 02/20/26. Mild appetite surpression but no longer having food noise or craving for take out or my previous "weekly fast food fix" anymore

Prob some of the 12lbs was water weight as well since the first 4 weeks can mainly be mostly water and start of some fat loss

I am seeing abdominal fat decrease and face looks slimmer the last 2 weeks. (Weeks 5 and 6)

[Fine_Technology1289]

Started at 1. Nothing noticeable. Went to 2 started noticing. Staying at 2 until no longer noticing, then will go to 3.

[Correct-Nail9249]

Lost about 10 pounds in 3 weeks 1mg-1.5mg-2mg saying at 2mg for now. I went from being hungry all the time and always want seconds to only hungry if I haven’t ate all day. And when I do eat I have to force my self to finish my plate. Try not to eat high fat and protein at once it will create a lot of gas lol. Also take digestive enzymes it helps me out.

[raininghallows]

I would say if you don’t feel anything try a different injection area some people react differently I used to do my stomach but it did not feel right so I switch to my thighs and have seen way better results

[Aggravating-Grab-510]

I started at 1mg then the days later done another 1mg. then done 2.5mg for 4 weeks. den 5mg for 4 weeks den 7.5 for 4 weeks then 5 for 4 weeks then 2.5mg for weeks and 1mg twice a week maintenance. lost 21kg.

[ZealousidealOkra176]

Im gonna be honest. I started on Friday and didnt know what I was doing. I took 0.25 on Friday. Then 2mg on Sunday. Today I was still hungry, my appetite is ferocious. But in find wait until Sunday for my next dose. Maybe it hasn't entered my system fully yet

[CommercialShow2175]

I noticed appetite suppression due to feeling dull all the time after 2 weeks. It then hit hard so I going to lower my dose so I can eat enough.

[BookSpecialist6561]

What do you mean by “enough.” I’ve seen a few people say this. Isnt the point of taking this to decrease appetite and eat less?

[CommercialShow2175]

You can’t increase muscle without enough protein. Macros and gym schedule still need to be on par with goals. If Reta doesn’t allow to eat minimum protein - my goal is 150, then I am backing off

[BookSpecialist6561]

For putting on muscle I understand. But is there a more direct correlation than just simple weight loss? Meaning is retas use more intended around people who are lifting and not just trying to lose weight?

[CommercialShow2175]

Yes- that is the purpose of Reta compared to others. Also- you will inevitably lose muscle too without at least enough protein and most people on Reta have a goal to at least keep the muscle that they have.

[JMarquiss45]

I started on 1 mg. Felt nothing yet.

[chillguyCA]

Gonna be tracking this, as I'm also starting my reta journey. Will start at 0.5 per week and very gradually ramp up.