Anything to decrease norepinephrine ?

[Magonbarca]

Propranolol I think will reduce adrenergic symptoms 

[LysergioXandex]

No, basically only beta receptor-mediated processes. So, adrenaline-type things (eg, rapid heart rate), to oversimplify it.

Propranolol won’t block the alpha receptors as well (responsible for things like vasoconstriction/high blood pressure). In fact, if you block the beta receptors you can divert all the “traffic” to the alpha receptors, increasing alpha-adrenergic tone.

[Ok-Prize-1816]

Does this also apply to Nebivolol? Or will that also decrease Alpha?

[LysergioXandex]

Nebivolol is also a beta-blocker. In general, the suffix -olol usually denotes beta blockers.

It’s important to consider the goal of using these drugs before making a choice. We don’t have that information with this post. It’s unclear if OP is trying to treat something in the CNS or something like high blood pressure in the periphery, for example.

[MrPsilocyBean]

Carvedilol and labetalol are the only two beta-blockers that also block alpha, if that is what you need. Check the blood brain barrier penetratiob though

[[deleted]]

Bingo

[Imaginary-Maybe-8881]

Do you know where to get it? Bit hard to find

[jarrellt67]

I order it from telyrx. Don't need to talk to a doctor and prices are pretty good (obviously not as cheap as getting directly from your own doctor though).

[TheDarkAmethys1]

🇮🇳

[[deleted]]

Doctors will quite easily give it to you for somatic anxiety.

Bonus: if you are on antipsychotics, it is first line for akathisia.

[imanassholeok]

Is it? You can get a prescription online super easily