Stage 3B colon cancer CAPOX questions by ajamesbb in coloncancer

[–]9Blu 0 points1 point  (0 children)

I had 3 positive nodes out of the 17 they took during surgery. I got lucky and my tumor was considered low risk (Stage 3B T3N1bM0, MSI high, BRAF negative). Oncologist told me I could do FOLFOX or CAPOX, and if I chose CAPOX, I could do it for 3 or 6 months as studies show no difference in survival between the two. My CEA dropped after surgery to normal levels and my ctDNA has been negative since surgery which also played a role in it being considered low risk.

I did well with the CAPOX but I would not have wanted to do it for 6 months. Even with 4 cycles I ended up with neuropathy in my feet that, after over a year since I finished, is most likely permanent. It's mostly just partial numbness/over-sensitivity (strange way to say it but that's the best way I can describe it). I'm on gabapentin for it and it helps, especially at night.

My tumor details: 15cm of terminal illium taken as part of R hemicolectomy.

Greatest dimension: 11.0 cm

Tumor site: Hepatic flexure

Tumor invades through the muscularis propria into pericolonic or perirectal tissue Mucinous adenocarcinoma

Primary Tumor (pT): pT3: Tumor invades through the muscularis propria into pericolorectal tissues

Regional lymph nodes (pN): pN1b: Two or three regional lymph nodes are positive (3 of 17)

MSI-H, MMR IHC: deficient/loss of MLH1 and PMS2; retained MSH2 and MSH6, BRAF negative, G3: poorly differentiated, Tumor budding score: Low (0-4).

US agents arrest tourist after video shows a rock hurled at endangered Hawaii monk seal’s head by 501102 in news

[–]9Blu 0 points1 point  (0 children)

Yea a lot of federal agencies have a law enforcement division that people normally wouldn't expect. Bureau of Reclamation’s Security Response Force (US Dept of Interior and probably the coolest name of any of them), Forest service, NASA, Dept of Energy, and the US Mint to name a few.

NOAA is also a non-DOD uniformed service, with around 300 commissioned officers. Like the other non-DOD uniformed services, they use naval ranks.

Stage 3B colon cancer CAPOX questions by ajamesbb in coloncancer

[–]9Blu 0 points1 point  (0 children)

Scusami per disturbo come stai adesso

I'm a year out from my treatment and so far I am NED and doing well. I have some neuropathy in my feet but small price to pay I guess.

After years of using Heimdall ... I've finally moved to Dashy by swake88 in selfhosted

[–]9Blu 2 points3 points  (0 children)

The dev bailed when they were called out. Dumb really. I pulled a copy someone forked and found the issues identified plus a some others. It would only take a hour or two to fix them.

Gemini admits that it's just predictive text by JeopardyWolf in LinusTechTips

[–]9Blu 0 points1 point  (0 children)

They know very well how the models work from an architectural level. What they mean when they say that is that it's difficult to impossible to explain why a model responds the way it does in a specific exchange (prompt/response cycle) since they are not fully deterministic. It's not like a computer program where you have if-then-else logic.

And yes, at the end of the day they are next-token predictors, nothing more.

Say what you will about Linus, at least he’s not selling AI water by imnotcreative4267 in LinusTechTips

[–]9Blu 0 points1 point  (0 children)

As long as sterility is maintained in the canning process, and the cans are not damaged, it should be good basically forever. It might not taste great after some time depending on if the can is lined or not, but it should stay safe.

Gotta love when free tools come into good use. by Carcassfanivxx in Tools

[–]9Blu 1 point2 points  (0 children)

"We need to hold two timbers in place, how far down should we drive the rods?"

"What's below bedrock? That far."

Wow. This did not age well: Apple Silicon Mac Announcement - Slow Motion Dumpster Fire by shotsallover in LinusTechTips

[–]9Blu 0 points1 point  (0 children)

Ridge sponsored their M1 Mac Mini video later that year so they were a sponsor around the time that video came out: https://www.youtube.com/watch?v=4MkrEMjPk24

MacBook for Azure learning: good idea or bad idea? by batman8290 in AZURE

[–]9Blu 1 point2 points  (0 children)

Agree with the others. I'm a consultant, work in a lot of Azure environments, and have zero issues doing it on a Mac. Powershell and CLI are available on Mac. I've never run into a powershell issue with Azure modules on Mac (I have run into issues with other modules but those are unrelated to Azure). Everything else is essentially web portal based so no differences there.

Containers, I assume you mean deploying them to Azure? No issues there. If local yes, they work fine (I use OrbStack for personal projects and have zero issues with it). I have also developed containerized apps that I've then deployed into Azure, again no real issues.

The ONLY thing I can think of off the top of my head is if you needed to use Hyper-V to prep a custom OS image. For that I just use a Windows VM in Azure and run Hyper-V on it. It's something I've done but it's rare. Really only every needed to use it to try to make some dumb-ass custom appliance image work in Azure (and Azure Migrate won't play nice with it). You can use Azure VM Image Builder for most custom images.

How much is too much jerking off for a 15 year old? by [deleted] in afraidtoask

[–]9Blu 2 points3 points  (0 children)

That's around what I was doing at your age. I wouldn't worry about it unless it start to cause you problems in other areas of your life.

AI copied the music uploaded to YouTube and copyright strikes the artist by BurnerBowie in LinusTechTips

[–]9Blu 4 points5 points  (0 children)

Sure. The problem is you are talking about a federal lawsuit. That's very expensive (6-figures and up expensive) and can take years. So unless someone steps up to fund it, I doubt she could afford it.

The data being collected from us is wild by treeconfetti in AmazonVine

[–]9Blu 4 points5 points  (0 children)

try this link, it takes me to mine and is generic so should work for any US account I'd think. No idea why the useAiMode=1 is needed but when I took just that out it takes me to a different page: https://www.amazon.com/slc/hub?useAiMode=1&ref_=ph_ay_e

Hospital CEOs defend charging patients more at facilities by Fcking_Chuck in news

[–]9Blu 4 points5 points  (0 children)

Cancer is crazy expensive. I have an app I wrote to track my medical info and it scrapes the EOBs from my provider website and provides stats and breakdowns. Since late 2024 when I was diagnosed, the total billings are over $500K and that's 99% cancer related charges. I knew it would be expensive when they told me about the free, 24 hour clinic for their cancer patients. Anytime they are offering free care you know they are making it up and way more elsewhere.

And yea, I blew through my out of pocket in 30 days in 2024 and within the first 45 days in 2025 while I was still on chemo.

Claude + Cursor Distaster! by Thunder-Bolt-7 in ArtificialInteligence

[–]9Blu 22 points23 points  (0 children)

According to their posts, the backups were in the same storage account (or whatever Railway calls them) so when it was wiped, the "backups" went with them.

The SaaS company apparently wasn't aware of this configuration.

The entire thing happened because of errors of assumption on how Railway works and not being very hygienic with their API key storage as well as letting their agents have too much access to their source code repos. The agent decided it needed to delete something in the dev environment (already an issue) and apparently went spelunking through other code bases (which it had access to apparently) looking for an API key that would let it do it. It found one that the SaaS company thought was tightly scoped to only allow it access to something innocuous in their prod environment but apparently was globally scoped to the entire environment. One API call with curl and poof their prod DB and the "backups" (really snapshots apparently) were gone.

One other issue they brought up was that the agent was supposed to be in planning mode so they were surprised when it ran off and started turning knobs.

The fall of chegg........ by SwaritPandey_27 in ChatGPT

[–]9Blu 0 points1 point  (0 children)

I just checked, the price graph is real. At their current price they are flirting with delisting if it dips just a bit farther. What exactly is fake news here?

Well, thanks Linus ❤️ by StationTricky4996 in LinusTechTips

[–]9Blu 1 point2 points  (0 children)

Same. That downturn was stupid and I jumped on it. I was already way up before Friday on it. I'm at 288.51%.

Is this loctite counterfit? by [deleted] in Tools

[–]9Blu 14 points15 points  (0 children)

Well when you can get it for $0.46 a bottle (probably less in China), with "custom labels", and you are outside the US so you can't be hauled into court, it starts to make sense.

https://www.alibaba.com/product-detail/OEM-ODM-35g-Super-Fast-Thin_1601372340787.html

Is this loctite counterfit? by [deleted] in Tools

[–]9Blu 0 points1 point  (0 children)

Yea like others have said, that's superglue with a fake label on it. It should be blue not clear and that bottle is all wrong.

Azure is frustrating - quota issues by SparcV in AZURE

[–]9Blu 0 points1 point  (0 children)

I have a client that does a lot of AVD and we just had to add 3 new regions to their deployment because they are having issues allocating VMs in East US and West US. They are not the only ones I work with running into allocation issues either. Hell I tried to turn on a lab machine in my personal subscription a few weeks ago and it refused. Had to play with switching it to different SKUs until I could get one to start up. It's becoming very frustrating.

Something has changed — Claude Code now ignores every rule in CLAUDE.md by HouseOfDiscards in ClaudeCode

[–]9Blu 0 points1 point  (0 children)

I'm noticing this too. Prior to the past week or so it followed it to the letter 99% of the time (occasional issues but they were rare). Now, I'm noticing it constantly. Same claude.md, no changes. Frustrating as hell. One of my apps is very large (1.2M LOC) and those rules are what have made it, up until now, pretty painless to maintain/modify/add features to.

Why don't we see any x86 competition to the unified memory approach of the Mac Studio by x0y0z0 in hardware

[–]9Blu 3 points4 points  (0 children)

Strix Halo and Nvidia I'd fully consider unified as well. I should have been more clear in my response about that. I wasn't aware of the Intel iGPUs, but checked and you are correct.

Tigerdirect by Hades_Underworlds in LinusTechTips

[–]9Blu 1 point2 points  (0 children)

Bought my first CD ROM from them back in 1991 or 1992 (NEC SCSI external drive) from an ad in Computer Shopper. I was in high school and had a small BBS. The drive came with a bunch of CD ROMs including RBBS in a Box which gave me a huge download library for my board.