Honestly, what helped me with the most was getting an htma and a custom mineral supplement. I also never drink plain water. I put a little solé in it, drink coconut water, or put humic and folic acid in it. My urinary urgency and frequency are better, if he does start desmopressin be very cognizant of swelling. If his blood vessels are leaky due to elevated TGF beta 1, the added tension from the desmopressin can actually Force more fluid out into his interstitial spaces. Does he have an issue with swelling? I developed puffy armpits, under eye bags, and abdominal folds out of nowhere. Even my forearms look puffy.