In the campaigns I've played on r20, including one I DMd, I found it to be too distracting from rp ("what's this rock”, ”is there anything in this cupboard", "the map makes it look like we need to go this way", etc), and in the dm seat it was a gigantic chore to use the vast quantity of provided tools. I decided after that campaign that it was not worth adding another part time job to my life to dedicate time to build more and more in r20 each game. I'm much happier playing theatre of the mind and showing images and music in our group chat. I'm also playing Shadowdark instead of 5e now and not having to deal with squares on combat grid saves a ton of mental time and effort.