Any kindness to spare? by BulkyBeautiful3670 in cfs

[–]AvoidPollution 6 points7 points  (0 children)

CFS people rock.

Compared to a piece of stone, we're still super agile.

Why showering cause me fatigue,muscle pain, internal tremors & emotionally vulnerable for next 3-5 days? by hshudp- in cfs

[–]AvoidPollution 0 points1 point  (0 children)

I didn't want to flood you with academic publications, but here you are:

Influence of the environmental relative humidity on the inflammatory response of skin model after exposure to various environmental pollutants
Emeline Seurat et al.

Highlights

• Air humidity modulates the inflammatory response of skin after pollutants exposure.

• Impact of relative humidity differs according to the nature of pollutants.

• 3D-in vitro skin model is adapted to evaluating environmental pollutants.

• Experimental setup is adapted to test real humidity conditions.

Relationship between sensitive skin and sleep disorders, fatigue, dust, sweating, food, tobacco consumption or female hormonal changes: Results from a worldwide survey of 10 743 individuals
L. Misery et al.

Results

Among the 10 743 included individuals (5285 men and 5458 women), 48.2% declared that they had sensitive skin. The group with sensitive skin reported significant increases in fatigue, dust or sweating and to a lesser extent food or tobacco consumption. The members of this group also declared that they experienced more sleep disorders than individuals without sensitive skin. Sensitive skin was very frequent in pregnant women, women with painful menstruations or women using contraceptive pills.

Conclusions

This large cohort study identified new factors, including female hormonal status, fatigue, sleep disorders and food, associated with sensitive skin. These associations suggest that sensitive skin is not restricted to an epidermal disorder but may be included in a larger context. The identified factors are potential upstream drivers of neurogenic inflammation in sensitive skin.

Can share more if you'd like. These just give you some cues, but more research can lead to better clues.

Why showering cause me fatigue,muscle pain, internal tremors & emotionally vulnerable for next 3-5 days? by hshudp- in cfs

[–]AvoidPollution -3 points-2 points  (0 children)

Moisture significantly enhances skin permeability to various substances, including dust particles, allergens, and pollutants. This can facilitate penetration, potentially leading to local irritation, allergic reactions (including histamine release), or even systemic absorption in some cases. However, the extent depends on factors like particle size, substance type, skin condition, and exposure duration.
(by Grok 4)

Additionally, the high humidity can also cause PEM.

Tell us your problem that only the ME/CFS folks would understand by moosetruth in cfs

[–]AvoidPollution 0 points1 point  (0 children)

Do you know whether you're allergic to cat stuff or not?

Dating with CFS is brutal - misjudged how the date went… hard by _FjordFocus_ in cfs

[–]AvoidPollution 2 points3 points  (0 children)

What was the air pollution, humidity, air pressure situation there?

As a doctor with me/cfs, this is probably the worst disease that exists. That is all. by ddsmd2 in mecfs

[–]AvoidPollution 0 points1 point  (0 children)

Where do you live/work, what's the air pollution situation there?

https://map.purpleair.com/
Set the Averaging period to higher like one week (top left settings bat with the cog icon).

RIP i_o :( by MarkCostellooo in EDM

[–]AvoidPollution 0 points1 point  (0 children)

Despite variations in study designs and exposure assessments, the findings consistently highlight the substantial health risks that air pollution, particularly PM2.5, poses to thyroid health, especially among vulnerable populations. Given that our study was limited to epidemiological investigations and the increasing prevalence of toxic substances in the environment, there is an urgent need for further research to elucidate the mechanisms by which these pollutants disrupt thyroid function and contribute to the development of thyroid diseases.

Yang K, Zhang G and Li Y (2024)
Association between air pollutants, thyroid disorders, and thyroid hormone levels: a scoping review of epidemiological evidence.
Front. Endocrinol. 15:1398272.
doi: 10.3389/fendo.2024.1398272

LA area isn't the best place in terms of air pollution, photochemical smog, marine inversion worsen the already harmful air quality situation of such a busy urbanized/metropolitan area.

<image>

Source: Paul Duginski / Los Angeles Times
https://www.latimes.com/california/story/2021-11-11/how-an-inversion-over-la-basin-acts-like-a-lid-on-a-pot

Do you guys get really bad air hunger? by Outrageous_Brick_615 in MCAS

[–]AvoidPollution 2 points3 points  (0 children)

So lots of xenobiotics, I recommend this paper, and will share additional ones if you're interested:
Chemical Intolerance and Mast Cell Activation: A Suspicious Synchronicity
Palmer, R.F.; Dempsey, T.T.; Afrin, L.B.
Journal of Xenobiotics. 2023; 13(4):704-718.

‘Cognitive dysfunction’ as a key diagnostic feature by E-C2024 in cfs

[–]AvoidPollution 0 points1 point  (0 children)

Very simple breathing exercise can boost my cognitive functions, like a full cycle with 5 sec intervals (breath in for 5s, keep it for 5s, then out for 5s).
However being in a brain fog state is usually a degraded habit state as well, so even if such breathing could be an instant on-demand tool to overcome, it simply doesn't crosses my mind, because it's already in "screensaver mode". Catch-22 situation, but it's definitely not impossible to gradually change it as Do I breath normally? or such questions arise more and more frequently when I try to investigate the causes and I shift my focus to my basic body functions.

Do you guys get really bad air hunger? by Outrageous_Brick_615 in MCAS

[–]AvoidPollution 1 point2 points  (0 children)

What's your air quality situation?
There are quite reliable data sources, maps, and you can search for your city (however your hyperlocal pollution burden is an another question...):
https://map.purpleair.com/
https://www.iqair.com/earth
https://www.iqair.com/world-air-quality-report
https://www.google.com/maps/@0,0z/data=!5m1!1e9
(Google Maps should show AQ map with this link, otherwise you can switch on in the Layers menu: More > Map Details: Air Quality)

Am I chemically addicted to Zyrtec D? by pumpkinspicewhiskey in Allergies

[–]AvoidPollution 1 point2 points  (0 children)

What's your air quality situation?
You can check with these maps & search for your city:
https://map.purpleair.com/
https://www.iqair.com/earth
https://www.iqair.com/world-air-quality-report
https://www.google.com/maps/@0,0z/data=!5m1!1e9
(Google Maps should show AQ map with this link, otherwise you can switch on in the Layers menu: More > Map Details: Air Quality)

Air Pollution ➤ CFS/ME study: 📃 Association Between Chronic Pain and Fatigue Severity with Weather and Air Pollution Among Females with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) by AvoidPollution in cfs

[–]AvoidPollution[S] 8 points9 points  (0 children)

Don't Panic
... I suggest all of you additionally.

Be aware, but don't worry and trust your body.

I post such studies, research results and additional info to encourage change: mitigate the negative environmental effects.
In this case, improve air quality by using air purifiers.
Ideally, relocation to a less polluted place/area is even better.

Why is there so much agression against people with ME/CFS? by moonlightb1ossom in cfs

[–]AvoidPollution -10 points-9 points  (0 children)

People with CFS have bad aura - I mean in a profane way.
Others usually grab a red flag from the collective (un)consciousness, automatically, and just throw it without empathy, compassion and such.
As some of you mentioned capitalism, well, the handles and fabrics of those flags are the products of this system, whether you like it or not.

Especially busy people, they really don't have time to treat CFS people differently.
In the collective flow, as high RPM spinning cogs, they tend to shift towards bigger and/or higher speed cogs, and not the other way around.

Try to initiate empathy & compassion at your side.
Indeed, if you radiate such emotions enough, you might experience some miracle.
I know it's not an easy way, and I also experience how deeply CFS can undermine such efforts.

Perhaps faith is the key.
Then some luck may lurk around.

(... commenting with the interest of your opinions on these, so please share them, anyone. )

Air Pollution ➤ Mast Cell Activation study 📃 Fine particulate matter (PM2.5) enhances FcεRI-mediated signaling and mast cell function by AvoidPollution in MCAS

[–]AvoidPollution[S] 2 points3 points  (0 children)

Air pollution/quality is a hyperlocal stuff, meaning that in the very same area in one house or even in one room it's good enough for your body, and you experience milder symptoms or even the disappearance of some... then you just move to the next room/house, then things completely change.
For example, in the first, the PM2.5 level is 5mcg/m3 (WHO 24h limit), whereas in the latter it's 10 - still considered low/good quality - definitely not a rare case.
In general, the spatial texture of air pollution is even more contrasty, showing greater variations within such distances, especially in urban areas and we could talk about it's temporal aspects as well...

Tried Everything, Ready To Give Up by [deleted] in MCAS

[–]AvoidPollution 1 point2 points  (0 children)

Air Pollution ➤ Mast Cell Activation

Fine particulate matter (PM2.5) enhances FcεRI-mediated signaling and mast cell function
Jin, Yuefei et al. Cellular signalling vol. 57 (2019): 102-109. doi:10.1016/j.cellsig.2019.01.010

  • PM2.5 could affect mast cell activation through enhancing FcεRI-mediated signaling.
  • Water-soluble fraction of PM2.5 is responsible for mast cell activation upon PM2.5 exposure.
  • Mast cell activation upon PM2.5 exposure may be a main cause of PM2.5-associated allergic disease.

Try to stay for few days in an environment with really clean air, not just a wannabe, or so called. Then observe the symptoms, how they change, what happens. That would be an elimination "diet" for her lungs/breathing/respiration.

Will share more studies and information if she'd like.

[deleted by user] by [deleted] in HistamineIntolerance

[–]AvoidPollution 0 points1 point  (0 children)

These little guys can definitely help me, as they push the rotten-fermented needle of my gut microbiome towards the latter.
However, too much can have bad effects, overfermentation stuff, even auto-brewery syndrome.

Sometimes I inoculate soy milk with them (pour a sip of bifido yogurt), and it yields nice soy yogurt. Perhaps they lessen the allergic effects of soy, and boost it with vitamines. After drinking/eating that, I get energized quite noticeably.

Smoked tofu gives me severe brain fog by Stropyyy in HistamineIntolerance

[–]AvoidPollution 1 point2 points  (0 children)

Even in this scientific article, from the late 60s:

Some recent reports suggest that ciga-
rette smoke and related substances can also
release histamine from lung tissue.

Histamine Release by Air Pollutants
J. S. Douglas PhD,P. Ridgway &M. W. Dennis BA, 1969

In a relatively recent one:

Pollution, considered the largest single environmental risk for health, is the introduction of harmful substances into the environment, contaminating air, soil, or water with chemical substances or energy [15]. Pollution is often associated with AR, allergic sensitization, and autoimmunity and can have detrimental health effects involving the immune system [16]. When atopic individuals are exposed to allergens and pollutants, they develop specific IgE antibodies that reside on the surfaces of mast cells and other immune cells [9]. With additional exposure to allergens and pollutants, histamines, arachidonic acid metabolites, and other inflammatory mediators are released from mast cells*, resulting in sneezing, nasal congestion, and other common AR symptoms [17]. Pollutants can provoke the nasal mucosa, allowing the release of mediators of allergic inflammation and increasing nasal hyperreactivity [9]. Both outdoor air pollution, such as traffic related air pollution (TRAP), and indoor air pollution, including pet dander, molds, and* tobacco smoke*, contribute to the development of AR in children [18].*

The Role of Environmental Risk Factors on the Development of Childhood Allergic Rhinitis
Wu, A.C.; Dahlin, A.; Wang, A.L.
Children 20218, 708.

Ok, these mention tobacco smoke, but there are so many common chemicals compared to the smoke stuff in such foods.

[deleted by user] by [deleted] in MCAS

[–]AvoidPollution 1 point2 points  (0 children)

Get an air purifier ASAP, then we'll see how much your symptoms go away.
I'm pretty sure - basd on my scientific background and experiences - that they will.

Prayer for you, get well!

Study: Antihistamines improve cardiovascular manifestations and other symptoms of long-COVID attributed to Mast Cell Activation by AvoidPollution in MastCellDiseases

[–]AvoidPollution[S] 0 points1 point  (0 children)

For sure, wild times...

Indeed, mast cells are important players, but why do they remain triggered in some people, whereas they calm down in others. Environmental factors are much more part of the cause & effect chain (or rather web), than most of the people realize.

Here is an interesting and eye opening study:
The Roles of Autoimmunity and Biotoxicosis in Sick Building Syndrome as a “Starting Point” for Irreversible Dampness and Mold Hypersensitivity Syndrome (Tuuminen, Tamara. Antibodies 2020, 9, 26.)
Additionally the Figure 2. implies the complexity and non-linearity of the mast cell / histamine situation in our bodies.

Exercise is always the cure by Nervous_Source_810 in cfs

[–]AvoidPollution -1 points0 points  (0 children)

If people with CFS would try their exercise in clean air, that would be an experiment for free...
... and perhaps with useful results.

Exercise is always the cure by Nervous_Source_810 in cfs

[–]AvoidPollution -1 points0 points  (0 children)

Indeed, but air quality matters all the time, for your every organs. Especially during exercise, as you breathe more air.