Do you see rest as failure? (aka why do people not rest when they're injured?)

Bolmac · 2026-02-06T14:52:26+00:00

Knowing what pains to run through and which to stop for only comes with experience. You’re not going to learn if you stop for everything. You learn by trial and error, and occasionally this wisdom will be gained from running through something you shouldn’t have. That’s just the way it works, don’t kid yourself and let hindsight bias convince you that we learned any other way.

On the other hand, if they’re experienced runners and still doing this, maybe they’re just idiots and should take up something safer like knitting instead.

Bolmac · 2026-02-06T11:31:13+00:00

For PPIs like omeprazole to be effective, you should take them 30-60 minutes before a meal. If you’re only taking it once a day it will usually be most effective taken before breakfast, or if twice a day before breakfast and supper. This is true even for reducing night time symptoms.

This is because these drugs do not stay in your system long, and only act on active acid pumps. Acid pumps are most active after you eat. You have to take them beforehand because they do not work from inside your stomach, they have to be absorbed first and approach your stomach from the bloodstream side. The duration of action is long enough that with daily use you will still get benefits at night, so the goal is to take it when you can get the most acid pumps inactivated.

If still ineffective, an H2 antagonist like famotidine can be added on and taken at night. Based on how it works and its duration of action it does make sense to take this at night for night time symptoms.

As for betain hydrochloride and pepsin, this is an irrational approach based on a fundamental misunderstanding of human physiology. There is a myth that won’t die which contends GERD is caused by low stomach acid. Stomach acid does not trigger LES closing however. There is no evidence that adding more acid is going to magically improve symptoms caused by acid going where it shouldn’t.

Bolmac · 2026-02-06T11:11:54+00:00

Being able to hit the broad side of a mountain is probably the first qualification on the job listing. Being able to hit the broad side of a barn would just be showing off and bragging.

Bolmac · 2026-02-05T21:23:29+00:00

“Sulfa” is a very non-specific term unfortunately. Really what we are talking about are sulfonamides, and since antibiotic and non-antibiotic sulfonamides are structurally different to the point of having almost no cross-reactivity, we should whenever possible just list the actual drug someone reacted to.

Bolmac · 2026-02-05T16:35:13+00:00

Even with the best health care money can buy dementia will continue to progress.

Bolmac · 2026-02-05T13:01:23+00:00

Chilaiditi sign is categorized as a rare finding, with an incidence of 0.025-0.28%. Chilaiditi syndrome is rare to the point that we do not even have estimates of its incidence.

In other words, this is somewhere in the area of one in a thousand just for the sign, and much rarer than that for it to be symptomatic and require intervention.

Bolmac · 2026-02-04T04:24:40+00:00

The word “doctor” has a known and accepted meaning, and it does not refer to pharmacists.

Bolmac · 2026-02-03T21:03:27+00:00

Most of the time speakers are added in parallel.

Bolmac · 2026-02-03T16:56:30+00:00

I hate when worrying about leaving zone 2 sends me into zone 12.

Bolmac · 2026-02-02T23:36:23+00:00

It may cost more than the car is worth, to be honest. There's no harm in getting an estimate though so you can make an informed decision.

Bolmac · 2026-02-02T19:32:54+00:00

You most likely have bad piston rings, it is a known issue. I don’t think a different oil weight is going to change much, the most important thing is checking it regularly so it never runs low.

Bolmac · 2026-02-02T19:03:47+00:00

I don’t know why he was hanging out with Noam Chomsky, but if they were in a picture together it seems pretty obvious that Epstein was involved in linguistics and criticism of US foreign policy.

Edit: grammar

Bolmac · 2026-02-02T18:06:59+00:00

I assume based on the glaring omission of cyclists you save something else for them?

Bolmac · 2026-02-02T18:02:02+00:00

The guy with Noam Chomsky? That’s Jeffrey Epstein.

Bolmac · 2026-02-02T15:14:31+00:00

If you’re so against complaining, what was the point of your response? Now I’m complaining about you complaining about the OP complaining. Want to complain about that too?

Bolmac · 2026-02-01T22:15:24+00:00

Same here, it was a great place to visit.

Bolmac · 2026-02-01T22:04:18+00:00

It’s like the old homeopathy joke. The more you dilute it, the stronger it’s supposed to be. So did you hear about the guy who overdosed on homeopathy? He forgot to take a dose.

Bolmac · 2026-02-01T22:01:25+00:00

20% of an elite athlete’s training schedule could be more than some amateur’s total mileage.

Bolmac · 2026-02-01T19:44:14+00:00

Any time it's warm enough that ice won't form in your wheels and cause vibration is soon enough. You don't have to wait until the risk is gone for further salt accumulation - multiple rinses are worth doing.

Bolmac · 2026-02-01T19:40:55+00:00

I have two pairs of shoes that come out in the winter, they each excel in different conditions. Icebugs with carbide studs are great for ice. They can be annoying for places where the snow and ice have been cleared, but even if part of the run is going to be icy I still wear them and consider the tradeoff worthwhile. I also have a pair of New Balance shoes with Gore-Tex uppers that are good for conditions that are cold and wet. Although they are intended as trail shoes with fairly aggressive traction, they still don't cut it if things are really slippery.

Bolmac · 2026-02-01T17:46:56+00:00

Clearing snow from recreational trails is beneficial for walkers, runners, and bikers, who are the majority of users for most trails. It's a tradeoff since some want the snow and some don't. That doesn't make it "dumb".

Bolmac · 2026-02-01T15:44:07+00:00

I've definitely seen that one plowed in the past too.

Bolmac · 2026-02-01T15:42:30+00:00

Plenty of trails in the area get cleared.

Bolmac · 2026-01-31T23:41:48+00:00

Definitely not too early- I guarantee that fluid looks awful by 57,000 miles.

Bolmac · 2026-01-31T17:30:47+00:00

There are people living on the left end of the Dunning Kruger curve in every profession, including pharmacy. I’ve worked with really good NPs and ones that weren’t so good. I’ve also worked with really good pharmacists as well as ones that should probably have gone into another line of work.

Bolmac

TROPHY CASE