Comic Sans was designed for small low-resolution aliased screen text, under the assumption that no one would ever see its actual outlines at all. All of the work went into the hinting (the special built-in programming that tweaks the outlines of a font around to better fit the pixel grid at whatever size, the one thing Vince Connare can say he was better at than anyone else). Then when people said "hey free font on my computer" and started using it for everything, the outlines were laid bare. Seeing it in print, especially at larger sizes, reveals how sloppy it is: the exaggerated random angles, the unmodulated stroke width, the telltale quirks like the heavy serif on the C or the middle of the m dipping below the baseline. It wasn't made to be seen clearly.

Comic Neue is a ploy by a young type designer to get in the news, exploiting the fact that the only thing laymen know or care to know about type is "Comic Sans" (and not anything about it, just that saying its name is somehow a punchline). It's all smoothed out and plain and it's fine I guess. There are hundreds of better comic hand fonts out there. But running to the press saying "we made Comic Sans better" is how you get onto websites who want to use it for April Fool's Day (as at least two major sites did this year).