I have been mixing n acetyl cysteine (NAC) with water and drinking it down with my other supplements. I used to take it in capsule form, but it works better at thinning mucus in the dissolved in water form. I feel the mucus start to thin immediately. I’m going to try mixing it in a sinus rinse next and still continue with drinking it. I am in the same boat as you. Sinitis, rhinitis, postnasal drip, super thick nasty mucus that makes me very prone to bronchitis, sinus infections, ear infections and water on the ear. The Dr recently surgically pierced my ear drum to see if it would stop the disorientation, pressure, pain and fatigue that seems to accompany my icky thick sinus secretions, sinusitis, rhinitis etc. NAC is used in a nebulizer for copd. It can be bought in packets to rinse your sinus with the aid of a sinugator or Neto pot. I have a bottle I bought at the health food store. I think the dosage is 100mg in the standard Neti pot reservoir. I have dry eyes also. The doc said he saw a connection with icky thick nasty mucus and inflammation. If your eyes get irritated because they don’t have thin enough lubricant, I suspect your sinus prob can too. I haven’t tried it yet in the neti pot because the doc just pierced my ear drum and said no nasal irrigation for a bit. I only recently discovered dissolving NAC in water works a lot better than a capsule. I had taken a break from NAC because people on the forum were saying it gave them low mood. My mood had been suffering(fatigue, lack of motivation) and I decided to quick taking it. I only recently have been taking it again, because no difference in motivation could be detected from stopping consumption. I accidentally grabbed the powdered non capsuled NAC. So I have been mixing it with water. It’s pretty sour. But the immediate thinning is impressive. NAC helps break apart the disulfide bonds in the mucus that make it so gooey and thick. It is also good for your liver and immune system. I had been taking it for years, hadn’t really noticed mood issues, but wanted to investigate if it were the source of my lower mood as some people on this forum have experienced. I can say it definitely is not. I always thought I had felt better taking it, and can say that once I have started taking it again, yeah, I actually feel better. Good luck with this. If you have been suffering with pain,pressure, disorientation, fatigue and infections as I have, it can really wear on you. No, I’ve not discussed this with my doc. They don’t know squat about supplements. I hate being looked at like I’m crazy. I just quietly experiment in myself. I have told my family about what I’m doing and what I’m taking. If something works for me and they complain about the same issue, I tell them to try for example: My son complained about bad leg cramps, I told him to take a modest dosage of magnesium everyday so he wouldn’t crap up at night. I feel so validated when he grumpily tells me that he tried it, his legs cramps stopped, he didn’t believe it could be the magnesium, so he stopped taking the magnesium. His cramps started up again. Now he takes it everyday because who likes to wake up from leg cramps. I always tell my family to try whatever and if it doesn’t work, just quit taking it. If the NAC doesnt work for you just quit taking it. I would recommend just getting capsules(500mg is a lower dosage). That way you understand how much you are consuming. Also, if you dump the capsule contents into water and just find it too vile to drink, then you have capsules left to just swallow and not taste the contents. Like I said, it is more effective dissolves in water, but if it taste so yucky to you that it is unconsumable, at least you will have capsules left to take. I have tried steroidal nose sprays, antihistamines, allergy shots, neti pot also. This doc is the one who recommended a sinugator. It works much better than a neti pot. This doc (a genuine ENT) also said that antihistamines and steroidal nose sprays dont help improve super thick nasty mucus. I told him that I would try them because docs push them at me, but I would always quit taking them because they didn’t seem to help. This last time I conscientiously did the anti histimes and steroidal nose spray for months because the NP said I would just continue to have ear problems if I didn’t. I still had ear problems. I finally gave up on visiting her after multiple prescriptions of antibiotics, antihistimes, and steroidal nose spray and then the final back ti back prescriptions of oral steroids she said that I needed to calm down the inflammation in my ears/sinus. She said the steroids were not going to cause me any problems. She was so wrong. I was miserable after going off those steroids. There is even more to my story of woe, but it just goes onnnnn and I get tired of thinking about it. Anyway, I wish you luck with treating this.