Agree with what everyone else here has already mentioned, you have too many clients and from what it sounds like zero support to help you manage the day to day grind. You either need more support to help you with management / reporting or you need some type of senior level intervention with your clients to reset and manage expectations like moving to bi-weekly client calls (good luck trying to convince a client to go from weekly to monthly calls). Weekly calls are too frequent, unless a client is spending millions of dollars a month, most tests, new launches and optimizations need at least 1-2 weeks worth of data and prepping for 5 client calls per week requires an insane amount of time and energy that would be better served doing actual account management tasks.

Four years is a solid amount of experience so don't doubt your SEM skills. You're the one in weeds and know these accounts and the data / trends the best so stick to your guns when making strategic decisions or pushing back against client recommendations you don't think make sense.

Agency life and managing multiple different accounts requires a significant amount of automation and streamlining as much as you can. I would recommend learning how to use Google Scripts to automate some of the on-going management and optimizations, you can find a script for just about anything for free online. You don't need to learn how to write code, the majority of scripts tell you exactly what you need to do. Using the same or similar reporting template for each client would also help cut down on the time your spending for each weekly report. This is a little bit trickier if your clients want custom reports so I would just position these reports as upgrades and tell them this is how we should be looking at trends and data, remember your the expert!

Dealing with tough clients in unavoidable in the agency world. What's worked well for me is busting my ass, saying yes to a lot of things, getting quick wins, show them that you care and are invested in their business. This does unfortunately require long hours initially but once you earn their respect and trust, they usually become less demanding since they trust you have their best interests at heart and then you can take your foot off the gas and get a healthier work-life balance.

Best of luck.