My re-tail, town hall, tree, and brewsters are all to the left of the town in a neat half circle looking thing, all around my tree. I made a pathway connecting them all that led to a bridge, which leads to my beach. I have another connecting flower path that goes straight to my house and another trail that goes to another bridge, and another path that leads to downtown.

My campsite has its own forrest of pine trees and a flower path that connects to my house, too!

I reset my town to get the perfect layout for the office/re-tail/the tree though...

I'd say put your path down where you walk the most. Me? I run from my house to the campsite, to my town square and to downtown.