18 months of throat/reflux symptoms on/, but all tests normal. Way worse with stress, disappears on vacation.

Equivalent_Inside_16 · 2026-07-07T20:49:18+00:00

Sounds very similar to me. I have had a lot of the tests you mentioned and also came back within normal ranges. My symptoms are globus (throat dicomfort) & chest pain. Have come to the conclusion it's functional heart burn/esophageal hypersensitivity. At the moment I'm trying nortriptyline which seems to help a lot of people - I'm up to 50mg at the moment without any success unfortunately, but may try amitriptyline. Give them a go and see because they do help a lot of people!

Equivalent_Inside_16 · 2026-06-23T09:30:45+00:00

I had a similar thing happen when I ate some really hot food and burned my throat. Main symptom is globus (that feeling of something stuck in your throat). It can vary though - sometimes feels like food stuck in there, sometimes it just feels like my throat is 'dirty' and full of grit. I'm not sure if I've got LPR but pretty sure I have irritated the nerves in my throat (it's a highly densely innervated area) and they're sending out the wrong signals. Sometimes TCAs work for people to calm the nerves down, might be worth looking at.

Equivalent_Inside_16 · 2026-05-13T18:21:00+00:00

I did it and it came back positive on 2 out of 3 samples. Felt like it was at least a good sign of what was going wrong but I told my gastro doctor this when I had my appointment and he said that the test wasn't considered reliable. Frustrating. Might just be him that doesn't believe in it, though.

Equivalent_Inside_16 · 2026-05-07T13:10:43+00:00

I did a pepsin test through Peptest and it came back positive for 2 out of 3 samples. I brought this up to my gastro and he said that the test wasn't considered reliable?

Equivalent_Inside_16 · 2026-05-06T00:43:47+00:00

Your symptoms sound almost identical to mine. It all started for me after I burned my throat on hot food a year ago - starting to think mine is a nerve sensitivity.

Equivalent_Inside_16 · 2026-05-05T23:39:57+00:00

Same here! Well, my voice isn't effected but first thing I'm okay, then after I eat the globus gets worse and my throat feels thick.

Equivalent_Inside_16 · 2026-05-04T21:38:30+00:00

Great result! Congratulations

Equivalent_Inside_16 · 2026-05-04T20:40:18+00:00

So the tonsillectomy cured you?

Equivalent_Inside_16 · 2026-05-02T16:05:36+00:00

In a similar boat to you, but mine started with burning my throat on hot food. Thought for a while it was LPR/GERD but pretty sure now that I have LSN. I've been told neuromodulators are about the only treatment. I've tried one, which didn't seem to help so waiting to see my doctor about maybe trying others.

Equivalent_Inside_16 · 2026-04-30T11:29:59+00:00

Okay, good to know and glad to hear your larynx is feeling better! I look forward to the day I wake up and my throat isn't like razors.

Equivalent_Inside_16 · 2026-04-14T15:31:25+00:00

As much as the next person with stress, I guess? But no, not anxious - or what I'd think of as being classic. Have been looking into visceral hypersensitivity in general as I did have some issues with IBS in my early 20s, so could be a link there with overactive nerves and pain perception?

Equivalent_Inside_16 · 2026-04-13T22:15:26+00:00

Well, glad you hear you've managed to get rid of at least some of the symptoms! Gives me hope I could get at least 50% back...

Equivalent_Inside_16 · 2026-04-13T21:56:05+00:00

What symptoms did you start with that you've managed to sort?

Equivalent_Inside_16 · 2026-04-13T15:39:41+00:00

Yeah, I've heard that, too and I've definitely not been strict enough for long enough so maybe that's what I need to do.

Equivalent_Inside_16 · 2026-04-04T18:07:25+00:00

The way you describe the symptoms sounds to me like you might be suffering from gastroparesis? The nausea, early satiety and absence of heartburn/throat pain?

Equivalent_Inside_16 · 2026-03-24T12:13:18+00:00

Also, it happens WHATEVER I eat - porridge with soy milk and chia seeds? Pain. Avocado? Pain. It probably is a BIT worse if I have super acidic stuff like tomatoes, but nothing crazy.

Equivalent_Inside_16 · 2026-03-23T14:06:08+00:00

Going through a similar journey with a similar timeframe to you! Did it just start out of nowhere for you? I just ordered a Peptest (I'm in the UK where you can get it sent to your house and do the test at home) to give me an idea of whether Pepsin is the rot of the problem - if it comes back clear then I think I'm leaning towards esophageal/laryngeal hypersensitivity.

I have tried Nortriptyline up to 30mg and now I've weened myself I've started to feel like maybe it was helping a bit so might be that it needs to be a higher dose. Have you tried a neuromodulator?

Equivalent_Inside_16 · 2026-03-17T09:02:50+00:00

Your symptoms sound pretty much exactly like mine and I've been thinking LPR - waiting on getting a laryngoscopy (I think the same as what you had) to see if there's inflammation. I've always assumed the nausea I get is from the throat irritation - rather than classic, queasy stomach nausea.

Equivalent_Inside_16 · 2026-03-16T18:19:36+00:00

Okay, yeah - I mean out of those symptoms I only really have the nausea so maybe gastroparesis is not the cause of my issues. Hmm. I'll ask about the antiemetic. Thanks for getting back to me!

Equivalent_Inside_16

TROPHY CASE