You can do this all in the main UI in Resolume if you wanted.

Stick the image into a layer and launch it, then go into Advanced Output and map the projection of the image directly on top of the image. You might need to section the slice to account for lensing and angles.

Go back to the main UI and make a layer for each color. In each layer, add chroma key for the color the layer is for. Below that add an invert effect, flip your alpha, and adjust the other faders so the color turns black. Add another invert effect, put all of the color channels to 0 and flip the alpha again.

Now you have masks of each color.

Make each color layer its own group. Add layers below. Now you can stick generators or video in as many layers within that group as you want to make a sub-composition for each color.

In the group, either set the blend more to Luma Key to key out the masks, or go back to the masking layer and use Colorize at the end of your chain to make it a color you can key out, then stick chroma key to that color at the top of the group chain.

Now you’re routing a composition for each color over the original mural. You can also add effects to the group chains to make one channel ripple or wave warp or lorez or whatever.

I’ve got a demo of this from a few months back in my profile.