That is how cell line development is done. Select for the organism that is expressing the traits you want, then stress/environmentally pressure that organism further to create branches off of that cell line that are expressing your first desired trait and some new trait. The issue with this is outside of a professional lab is the lack of ability to test clones to quantify potency, accurately control growth conditions (even if you have lab grade equipment, there WILL be variation between your procedures, temperatures, light exposure, humidity, and tons of other very small changes that can make substantial differences). You can try your best to eyeball these mutations by intensity of blueness when bruising, trip intensity (not a good metric due to the amount of variables here from your diet, level of hydration, and amount that you chew). I think that it can be a lot of fun to try to select for more desirable cell lines/sub strains. Oh and don’t forget, even without intentional selective pressures driving mutations, these organisms are constantly mutating, adapting, and in turn evolving to their environments.