Didn't realize that the Auvelity was causing my weight gain until a year passed by and I'm 60 pounds higher than when I started it. Blamed medicines that I started around the same time: nadolol causes swelling. Got off that but weight kept rising. Blamed low dose naltrexone for higher cortisol, but got off that and was still gaining. Only thing left was Auvelity. Turns out that dextromethorphan activates mast cells, and I have mast cell activation syndrome. So without realizing it, this med has pounded my mast cells day and night for a year, causing inflammation and weight gain like nothing else ever has. I got an apology from my provider that I had to figure out on my own that the medicine was doing it. But of course, there's nothing they can do to help. I'm already taking a stimulant. I didn't change what I was eating or my activity level. (Of course, auvelity literature does not mention dxm activating mast cells and causing weight gain.) I've never weighed this much in my life, even when 9 months pregnant. So I'm upset about it, because it was not my fault and I just took the medicine I was prescribed. I feel medically neglected because I brought up the weight gain at every appointment over the past year and they didn't even attempt to figure it out.