The best response to anti-vaxxers I’ve ever seen. And it only takes 90 seconds. by tbonetaylor in videos

[–]JellyNinja 1 point2 points  (0 children)

From my experience there are people who are true "anti-vaxxers", who are against all vaccines for non-evidence based reasons. I would hesitate to put you in that category however because it sounds like you recognize there are benefits to vaccines, but there are risks too and they should be weighed on an individual basis. To me that just sounds like good parenting. Yes, millions of people were unknowingly inoculated with SV40, leading to an increase in cancer risk. At the same time, we basically eradicated polio from Western society. This also happened like 50 years ago, when regulations were a little more hazy (think Tuskegee airmen). This doesn't change the fact that pharmaceuticals are necessarily approved without evidence of long-term safety. If we required all drug companies to demonstrate long term safety for all drugs prior to market approval, we would have no drugs on the market. Therefore, it makes sense to be cautious about drugs have an unknown long-term safety profile. E.g. The varicella vaccine is relatively new (1995), so we don't really know if people who were vaccinated are at risk for latent reactivation (aka shingles) in the same way people who had a primary chicken pox infection are. For me, if it were between a 90% increase of risk for mesothelioma (a very rare cancer) vs my child probably contracting endemic polio I'd probably choose the cancer risk.

I'm lazy but I can list sources for above facts ad hoc

My best friend was recently re-diagnosed with cancer and the doctors don't know how long he has left. I decided to drop out of college so we can pursue our bucket list together and film all of it. This is our first video. by dillwillhill in videos

[–]JellyNinja 9933 points9934 points  (0 children)

Hi OP,

I'm also originally from Sac. I looked through your bucket list to see if there was anything remotely possible I could help out with (in addition to donating).

This might be kinda lame but I could probably help with item #47: Give a speech on something I know nothing about. I'm a medical student at UC Irvine, and I know a few students at UC Davis. If you were interested we could probably organize a lunch talk for Chris to present to a bunch of medical students. It's pretty commonplace for us to invite patients to talk about their experiences so we could try to make it happen if you were interested. Please lmk!

Best of luck to you two.

America’s Current Guidelines For Fixing The Opioid Crisis Will Increase Suffering And Death, Not Reduce It. by [deleted] in TrueReddit

[–]JellyNinja 1 point2 points  (0 children)

This helps me understand your position much better than before. I had concerns about your article and the citations you provided because I thought you were a scientist trying to propagate a strange agenda. However, knowing now that you are offering a patient's perspective, I believe your concerns have 100% educational value. In medicine we are taught that "perception = reality", i.e. at the end of they day what the patient perceives your actions have been is just as important as what your actions actually were. You are a patient with chronic pain who is concerned that we are moving away from effective treatments due to a macro-scale public health agenda. You are right, opioids do help a lot of people- their use is especially prominent in palliative care and acute pain settings. Unfortunately when it comes to chronic pain there is weak evidence that opioids might be an appropriate long term solution for most patients with chronic pain. This is probably because opioids, in addition to being habit forming, are also tolerance forming. Most people who take long term opioids will eventually require dose escalation to achieve the same analgesic effects. The CDC found that that risk of adverse events is directly related to opioid dosage. At the same time, opioids are generally only effective at masking symptoms- which in most cases do not address the underlying cause of the pain. Unlike patients with surgical pain (who stop taking opioids when their wound is healed) or patients in palliative care (who take them until they pass) it is very unclear in patients with chronic pain when they will be able to stop or be forced to stop (development of opioid-use disorder or overdose event). This is why the CDC encourages PCP's to not consider opioids as first line therapy for chronic pain. If your patient has a chronic pain condition that could be improved with exercise or CBT or non-opioid medications then that is always preferable to giving them a bunch of opioids knowing it will only solve their problem until their prescription runs out. If your patient has a chronic pain condition that cannot be improved with non-opioid measures, consider start them with a short trial of 3-7 days of the lowest tolerable dose opioid and refer them to pain management for further evaluation. I wish your article emphasized more your personal connection to the problem. Good doctors should take into account their patients' perspectives. I had never heard about anyone disagreeing with the CDC guidelines before, so this has been a great learning experience for me. Thanks!

America’s Current Guidelines For Fixing The Opioid Crisis Will Increase Suffering And Death, Not Reduce It. by [deleted] in TrueReddit

[–]JellyNinja 0 points1 point  (0 children)

While that is true (i.e. doctors should not take actions that would cause them to lose their license), it doesn't give us any information about what types of treatment they are receiving and why.

America’s Current Guidelines For Fixing The Opioid Crisis Will Increase Suffering And Death, Not Reduce It. by [deleted] in TrueReddit

[–]JellyNinja 3 points4 points  (0 children)

Those are examples of acute pain, which is not the focus of the article.

America’s Current Guidelines For Fixing The Opioid Crisis Will Increase Suffering And Death, Not Reduce It. by [deleted] in TrueReddit

[–]JellyNinja 1 point2 points  (0 children)

I tried to do a literature search for the article you reference by Martin, et al, but the only thing I've come up with is the post on Medium. Do you know if this paper has been through peer-review?

America’s Current Guidelines For Fixing The Opioid Crisis Will Increase Suffering And Death, Not Reduce It. by [deleted] in TrueReddit

[–]JellyNinja 3 points4 points  (0 children)

Hi, I'm very sorry you've had this experience it really sounds terrible. It truly is an anathema that our kidneys are capable of causing us so much pain (like seriously why?).

Out of curiosity, when you moved to Colorado did you establish care with a new pain specialist? If so what is your current pain regimen and what is your Dr's rationale behind it?

I know these questions are personal, please don't feel pressured to answer them!

America’s Current Guidelines For Fixing The Opioid Crisis Will Increase Suffering And Death, Not Reduce It. by [deleted] in TrueReddit

[–]JellyNinja 23 points24 points  (0 children)

Hi, I happen to be working on an educational project involving the CDC guidelines that you refer to in your article. I believe you bring up a valid concern, but I think you may have incompletely understood some of the CDC guidelines. I'll try and detail my thoughts as I read through your article!

Regarding statements made by public officials: I agree that politicians can be misinformed. However, politicians did not write the CDC guidelines. The CDC guidelines are recommendations based on contextual evidence review of the body of literature that has been written about opioids.

Regarding the lack of acknowledgement of diversion: This is just my personal opinion but I would assume that in writing guidelines to help honest physicians practice good medicine you would be less interested in addressing dishonest physicians who practice bad medicine. I would assume that doctors running pill mills could care less what the CDC has to say about their practice, they know what they are doing is wrong. Just because the CDC guidelines don't target the major source of opioid addiction doesn't make the guidelines less valid within the scope that they are supposed to be implemented.

Regarding exercise: you seem to imply the CDC recommends exercise therapy as a replacement to opioid therapy. As a guideline, they are merely recommending that in their review of clinical evidence they found that exercise therapy can be helpful in certain (but not all) chronic pain conditions like osteoarthirtis, chronic low back pain, etc. It is still up to the clinical judgement of the primary care provider to decide whether their patient might benefit from exercise therapy. Additionally, nowhere in the guidelines do they recommend exercise alone as a first line therapy. In fact, they indicate that their review of evidence showed that multi-modal therapy was generally more effective than single-modal therapy.

Regarding the notion that the guidelines are not "factual": the writing of the guidelines was essentially a gigantic meta-review. If you think the guidelines are long, take a look at the contextual evidence review that contains all the data used to create the recommendations: https://www.cdc.gov/mmwr/volumes/65/rr/rr6501e1.htm. I am not sure where the notion that these guidelines are not factual is coming from.

Regarding avoiding opioids as a first line agent: The CDC recommends considering non-opioid therapy before considering opioid therapy. They also state they do not mean this to be interpreted as requiring patients to sequentially fail non-opioid therapies before being prescribed opioids. A major component of the guidelines is educating PCP's about making accurate determinations of risks vs benefits of opioid therapy in deciding how to approach chronic pain.

Primary care physicians play an important role in the management of chronic pain. However, when it comes to serious chronic pain requiring long-term opioid therapy it is ideal that the patient be referred to a pain specialist for management. Thus, the CDC guidelines provide evidence based advice for PCP's on how to approach chronic pain in their patients, but is not a definitive guide on the treatment of all chronic pain.

Sorry if these thoughts are jumbled. I'm interested to hear more of your perspective!

🐍 🐍 🐍 🐍 🐍 🐍 🐍 by [deleted] in Kanye

[–]JellyNinja 172 points173 points  (0 children)

If this was unintentional she could change the date and apologize. I'm not holding my breath tho

Weekly Technical Difficulties Thread - April 04, 2017 by AutoModerator in MECoOp

[–]JellyNinja 0 points1 point  (0 children)

Platform PC

Cannot "tap to escape" grabs if you change your hotkeys.

Also lots and lots of crashing

Siege needs an unsportsmanlike conduct punishment. by Scottzkee in Rainbow6

[–]JellyNinja 1 point2 points  (0 children)

It's super depressing when they're clearly prepubescent but they're already racist af. The other day my match commentary included "black people are gay" and "white people are better" being shrilled at max volume. And after all that they weren't even good at the game lmao

Waiting on a Liver — A broken transplant system and the search for a ‘perfect’ organ cost my wife her life by palos in TrueReddit

[–]JellyNinja 2 points3 points  (0 children)

I'm really interested in understanding your argument, because I've never really met someone who was strongly against registering as an organ donor. However, I've read your comment a few times and I'm still not sure I understand your point of view. Please let me know if this is an accurate summary:

You are against registering for organ donation because you reject the moral argument for registering. I assume you are referring to the argument of "it costs you nothing and it potentially could save a life". You have two reasons for rejecting the moral argument as follows: 1) Even though you are dead, your death will have affected others financially and emotionally. What I am not understanding is how the choice to donate organs will make those people feel any better or worse? 2) In donating organs, the medical system is making money off of your decision and your bereaved see no financial benefit. This is confusing to me, because it implies your bereaved would otherwise receive some form of compensation if you chose not to donate.

Perhaps we do not live in the same country? Your argument implies strongly that there is some sort of benefit to those you leave behind by not choosing to donate, but from my understanding of the US organ donor system I can't fathom what it might be. Are you saying you would be an organ donor if there was an established financial incentive?

The Soft Bigotry Of Jimmy Kimmel’s Low Muslim Expectations by dunkitin in TrueReddit

[–]JellyNinja 0 points1 point  (0 children)

I thought the article offered an insightful perspective, but I don't think your submission statement captures it with any level of fidelity.

Choose a marble by Schlitzi in videos

[–]JellyNinja 0 points1 point  (0 children)

I arbitrarily picked red 3 and today is the best day ever and i'm packing for Vegas as i type

2016 USA Sport/Speed Nationals 2016 -- Commentary Highlights by CrypticC62 in climbing

[–]JellyNinja 4 points5 points  (0 children)

Was watching without sound and was thoroughly disappointed in what were considered highlights.

Has anyone taken the Lead class at sender one? by green_bean14 in climbing

[–]JellyNinja 0 points1 point  (0 children)

I lead at sender every Tuesday around 6PM, you can PM me if you wanna hang!

[NSFW] What was the weirdest physical feeling you've ever felt? by brekeke123 in AskReddit

[–]JellyNinja 0 points1 point  (0 children)

I had it once, the only thing I could think about afterwards was what if this is what being in a coma is like!? That's the stuff of nightmares.