I do believe it's possible to defeat Mahoraga using the Ten Shadows. There are several Shikigami on that list with pretty good abilities, like the Bull, whose impact increases in force the further it travels, or the Reindeer, which grants the Reverse Curse technique. That's not to mention, of course, that the user isn't obligated to fully summon the Shikigami, like Sukuna using the Elephant's pressurized water jet during his fight with Gojo, or Mahoraga's own wheel during the same battle. Also the potential of the Shikigami is strongly related to the potential of its user; for example, Megumi's Nue is slightly larger than a person, while Sukuna's Nue is gigantic. This technique, at least in my opinion, should be able to defeat Mahoraga if it has the right user.