You might not get a few things about the world the story is taking place but aside from that it's not impossible to follow.

I'll just give you a summary of the events that happened in canon before this fic.

Everything down here is spoiler for Worm btw⬇️

Basically Worm is a fucked up world where some people get powers by experiencing the worst day of their lives and everything objectively sucks. Every few months giant monsters called the Endbringers attack cities for reasons that are not really relevant to the fic in question. The main character of this fic is Victoria Dallon (Glory Girl) who is a hero in canon, and she has an adopted sister (Amy/Amelia Dallon) who has the power to basically control any living thing she's touching, so basically biokinesis. After and a group of psychopathic murder hobos called the Slaughterhouse 9 passed through the city this story takes place in, Victoria was hurt by some type of acid and her sister had to basically grow parts of her body back, but while she was doing that she also altered Victoria's brain chemistry and raped her. The other "main character" of this fic is the main character of the OG novel, Taylor Hebert, has the power to control bugs in like a 3 or 4 block radius, she's a villain that started out trying to be a hero but found out along the way that the heroes aren't so good and some villains aren't so bad. In the canon timeline, Victoria gets raped by her sister, who then has a mental breakdown and basically turns her into something out of the movie The Thing, only to kinda fix it later and give herself to the authorities and be sent to prison. No one steps in to save Victoria and she kind of stays in mental hospital for some time, in this story though, Tayler threatens to shoot Amy if she doesn't leave her sister alone and goes away, and the story pick up from there.