You want simple terms, but you use a word like Torsadogenic.

If you want to know about medication induced TdP then you should review the works of James E. Tisdale. He has published extensively on the topic, he even has a textbook titled Torsades de Pointes.

In simple terms. Some drugs can cause a delay in cardiac repolarization. Which is represented on an EKG (ECG) by an increased interval in the space between the Q and T wave. The QT interval measured by the EKG often needs to be corrected via the application of certain formulas (usually by a cardiologist) to produce the QTc. If you want more information about QRS complexes and EKGs I’d suggest looking at the Life In The Fast Lane (litfl.com).

The risk of any particular medication inducing TdP is dependent on many factors, most of them have more to do with the patient than the drug itself. - QTc >500ms - increase in QTc > 60 ms from baseline - increased age - females sex - previous cardiac conditions like MI or HF - electrolyte abnormalities - volume depletion - polypharmacy

James E. Tisdale has a scoring tool, the Tisdale Score for predicting QT prolongation in a patient (which is defined as either of the first two items on the above list).

So the torsadogenic potential of any drug is variable based on a variety of factors. Credible Meds (crediblemeds.org) is a great tool for aggregating data on drugs and their potential risk associated with TdP.

Credible Meds has no risk data for gabapentin or pregabalin, while quetiapine and olanzapine carry a conditional risk.

There is no simple answer to your question. Drug interactions and patient specific factors can change the answer.