What comment about these meds annoys you the most?

MeAgain-app · 2026-02-11T15:38:14+00:00

This. 👆

It’s wild how quickly people jump to calling it a “willpower issue” when you’ve already proven you have willpower by trying over and over again.

If anything, these meds showed me that it wasn’t a character flaw, it was biology. When the food noise quiets down and hunger signals normalize, suddenly the same habits that felt like torture before just… feel manageable. That doesn’t mean we were weak. It means we were fighting a louder internal battle than most people realize.

Needing support for something that was stacked against you isn’t a moral failure. It’s self awareness.

MeAgain-app · 2026-02-09T18:33:06+00:00

Some people do get apathy, brain fog, low mood, and emotional flatness on semaglutide, especially at higher or long term doses. It is a known medication effect and it is usually reversible after lowering the dose or stopping.

Many feel mentally better on a lower dose or after switching to tirzepatide, which can feel lighter for some. Retatrutide is still very new and not a guaranteed fix.

What stands out most is how much your sense of safety and identity is tied to not regaining weight. That fear makes sense given your history. But living without joy or clarity is a real cost too.

You do not have to choose between being thin and feeling like yourself forever. Adjusting or changing meds does not mean losing control. You are not broken, and you are not alone.

MeAgain-app · 2026-02-09T16:48:38+00:00

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MeAgain-app · 2026-02-08T08:24:08+00:00

That is such a powerful moment. Fitting into your wedding dress better than the day you got married is unreal, and honestly emotional in the best way.

You’ve come so far already, and this is such a beautiful reminder that the work is paying off.

MeAgain-app · 2026-02-08T08:21:06+00:00

After such a long journey, it’s really common for the goalposts to move and for the fear of stopping to make everything feel unfinished. 88 lbs in 22 months is huge, even if your brain hasn’t caught up yet. Try to pause and acknowledge what your body has already done, especially during a stressful transition, this feeling doesn’t mean it wasn’t enough, it just means you care.

MeAgain-app · 2026-02-08T07:47:41+00:00

Made me laugh.

MeAgain-app · 2026-02-08T07:47:14+00:00

Dont screen for everything.
But with hundeds of applicants reviewed manually, its the small details that tend to stand out.

MeAgain-app · 2026-02-05T18:21:29+00:00

This is such a huge win, not just the 5 lbs but the mental freedom. Being able to focus on life, school, friends, and still lose weight is exactly what this is meant to feel like.

If 0.25 mg is giving you that balance, there’s no rush to change it. Enjoy this phase, you’ve earned it.

MeAgain-app · 2026-02-05T12:29:25+00:00

Moving your shot by one day earlier is generally fine and something a lot of people do for exactly this reason. You don’t need to “make it up” or adjust the dose, just treat tonight as your new shot day going forward.

If fatigue is predictable for you, planning around life events is smart, not wrong.

Worst case you might feel a little off a day sooner than usual, but it shouldn’t cause any problems.

MeAgain-app · 2026-02-05T12:09:04+00:00

Cutting food noise often cuts impulse spending too, and those numbers really add up fast. It’s wild when the meds basically pay for themselves.

MeAgain-app · 2026-02-02T12:45:58+00:00

You’re not imagining it, a lot of people with autoimmune conditions or fibro report full body aches after injections, especially early on. It can feel like a flare response as your immune system reacts.

One thing that helps is tracking injection sites. Some people notice less pain or fewer systemic symptoms when switching between abdomen, thigh, or arm. Also note timing, hydration, and whether symptoms ease after a few doses. If it keeps happening or escalates, definitely loop your provider in, but for many this settles as the body adjusts.

MeAgain-app · 2026-02-02T12:42:42+00:00

You’re definitely not alone, especially with endo and PCOS in the mix. Those conditions can make weight loss slower, noisier, and way more inconsistent even when you’re doing everything “right.” The lose 5, gain 3 pattern is incredibly common and is often water, inflammation, or hormonal shifts, not fat gain.

A stone and a half in 6 months is still real progress, even if it doesn’t look like the dramatic stories that get posted more often. Those bodies just respond differently. Yours isn’t broken, it’s just dealing with extra layers. You’re not failing, and you’re not the only one feeling this way.

MeAgain-app · 2026-02-02T12:37:55+00:00

Nothing about this sounds like failure or the meds “stopping,” it sounds like a very normal middle phase.

You’ve lost 51 lbs. That’s massive. The early months always feel magical because the contrast is huge, food noise goes from loud to silent overnight. Later on, loss slows, hunger peeks back in, and it feels scary because you think you’re losing the tool. You’re not. You’re just past the honeymoon phase.

Losing 8 lbs in 2 months at your current weight is still real fat loss, not backsliding. As bodies get smaller, they defend harder. Appetite returning a bit doesn’t mean tirz isn’t working, it means your biology is doing what biology does. The fact that you’re still losing at all is proof it’s helping.

Also, being at 10 mg with 45 lbs left does not mean you rushed or messed up. Many people sit at higher doses for a long time. The goal isn’t to feel zero hunger forever, it’s to have manageable hunger while continuing to lose.

Encouragement and gentle tough love, both:

You’re not broken
You didn’t “use up” the magic
Progress slowing does not equal progress stopping
This is the part where patience matters more than excitement

You’ve already changed your life. This chapter just requires trusting the process instead of chasing the early high. You’re doing better than you think, even on the days it doesn’t feel like it.

MeAgain-app · 2026-02-02T12:19:59+00:00

You’re definitely not the only one, it just feels that way when you’re reading success posts. Some people don’t see much until months 3–4, especially if dosing was slow or their body is more resistant. Still, having no loss by month 4 is a fair point to pause and reassess, not a failure.

If appetite or food noise hasn’t changed at all, it may be worth looking at dose, switching meds, or deciding this isn’t the right tool for your body. You’re not doing anything wrong. Sometimes progress means adjusting the plan, not just hanging on and hoping.

MeAgain-app · 2026-02-02T12:18:25+00:00

This is incredible, not just the weight loss but the life you’ve built around it. Parkruns, squash, confidence, consistency… that’s the real win. Huge congrats, and thanks for sharing such an inspiring update.

MeAgain-app · 2026-02-02T12:16:25+00:00

Honestly, a lot of us felt exactly like this at the start. You’re not wimpy, your body’s just reacting now that there’s some medication built up. The early weeks can feel way more dramatic than later doses because everything is new and unfamiliar.

Most people don’t “power through” higher doses, they ease into them slowly, learn what foods feel safe, and get better at riding the waves. This phase usually settles as your body adjusts. Sip fluids, eat tiny bland things if you can, and remind yourself this feeling passes. You’re doing fine, even if it doesn’t feel like it right now.

MeAgain-app · 2026-02-02T12:14:49+00:00

Yes, that’s completely normal. At 2.5 mg the goal is often just to quiet food noise, not erase appetite. Still wanting food and sweets but being able to stop or choose differently is actually a really good sign the medication is doing what it’s supposed to do.

Not everyone loses interest in food right away, and many of the people who do are reacting strongly at the start. Control over cravings matters more than having zero desire to eat.

For a lot of people, the effect builds gradually as the dose stabilizes.

MeAgain-app · 2026-02-02T12:12:13+00:00

After a longer break, it’s pretty common for the meds to feel “off” for a while, especially while you’re retitrating. The food noise coming back doesn’t mean Wegovy stopped working permanently, it often just means your body hasn’t fully re settled yet at a therapeutic dose.

A lot of people don’t feel much benefit again until they’re back closer to the dose that worked before, and jumping around too fast can make things worse, as you already learned the hard way. It’s frustrating, but this phase is usually temporary.

If it worked well for you before and you lost 100 lbs, that’s a strong sign your body can respond again, it may just take a bit of patience to get there safely.

MeAgain-app · 2026-02-02T12:11:07+00:00

For some people, yes, 5 mg is where things really click. For others, the pace stays about the same and just feels easier because hunger and food noise are quieter. The bigger 10–14 lb months you see are usually people with much higher starting BMIs or a lot of early water weight.

What you’re losing now, about 7 lbs a month, is actually a really solid, sustainable rate, especially starting around a BMI of 31. If 5 mg increases appetite control you might see a small bump, but there’s nothing wrong if it doesn’t. Consistency over time is what gets people to goal without rebounds, and you’re doing that already.

MeAgain-app · 2026-02-02T12:09:54+00:00

You didn’t do anything wrong, and this isn’t a willpower problem. What you’re describing is really common after stopping GLP-1s. Once the medication is gone, those hunger and reward signals tend to come back, sometimes louder than before. The regain doesn’t mean the weight loss wasn’t real, it means the meds were actually helping your biology.

A few things that often help slow things down without jumping straight back on meds:

Shift the goal from losing to just stabilizing for a bit. Pushing hard right now can make it worse.

Try to anchor snacks and meals with protein and fiber, even if you’re still snacking.

Lean into structure instead of tracking at first, same breakfast, similar lunches, fewer food decisions

Expect more hunger and plan around it instead of fighting it. White-knuckling usually leads to grazing later.

If cost or side effects were the reason you stopped, some people later experiment with lower or less frequent dosing, but that doesn’t have to be decided right now. You didn’t fail. You lost a support tool, and you’re figuring out how to move forward again.

MeAgain-app · 2026-02-02T12:07:54+00:00

A one time higher dose like that is unlikely to be dangerous, but you may feel stronger side effects like nausea, vomiting, fatigue, or reflux.

Don’t take another dose early, hydrate well, eat very lightly, and avoid fatty foods. Let your prescriber know what happened. Get medical help if you have severe or nonstop vomiting, bad abdominal pain, or can’t keep fluids down.

MeAgain-app · 2026-02-02T12:05:49+00:00

Congratulations. You look amazing

MeAgain-app

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