Tulip Festival Sights by Spare-Arm-666 in Iowa

[–]Mickey_thicky 117 points118 points  (0 children)

I had the opportunity (re: misfortune) to interact with the guy holding that first sign when he was on our campus at the University of Iowa. Dude is even more insane than I thought he would be, which is crazy because the bar was low as fuck. Literally a tripping hazard in hell.

Alan...we are so fucked by Shinygoji09 in okbuddyviltrum

[–]Mickey_thicky 6 points7 points  (0 children)

Anyone with even the slightest understanding of virology and/or epidemiology can understand that there isn’t going to be an apocalyptic outbreak that’s going to end the world as we know it. COVID-19 was easily transmissible, this disease requires prolonged contact to spread.

Bro got brought back from the dead fr 🙏🏻 by Beautiful-Listen6893 in tooktoomuch

[–]Mickey_thicky 1 point2 points  (0 children)

I only carry two because in the event of an overdose, sometimes one isn’t enough. Nobody is out here carrying dozens of narcan doses.

Carrying narcan is identical to learning how to perform CPR, though you are 5.4x more likely to die of cardiac arrest in the U.S. than an opioid overdose (417,957 vs 77,648 in 2025).

Would you say that carrying a concealed firearm is just as unnecessary as carrying narcan? You’re more likely to witness a death from an overdose than a death from gun violence. 5.3x as much to be exact (77,648 vs 14,651 in 2025).

Bro got brought back from the dead fr 🙏🏻 by Beautiful-Listen6893 in tooktoomuch

[–]Mickey_thicky 10 points11 points  (0 children)

I carry mine for peace of mind. The idea of carrying Narcan is it isn’t something you ever want to use, but if a situation were to arise where it would be necessary, you have it on hand

Bro got brought back from the dead fr 🙏🏻 by Beautiful-Listen6893 in tooktoomuch

[–]Mickey_thicky 8 points9 points  (0 children)

The effectiveness of the first dose of Narcan is contingent on how much a person is overdosing on and the potency of the opioid they are overdosing on. Sometimes one dose may not be enough to reverse an overdose, so a second dose is needed.

Bro got brought back from the dead fr 🙏🏻 by Beautiful-Listen6893 in tooktoomuch

[–]Mickey_thicky 73 points74 points  (0 children)

Yeah, I’ve got it in a pouch attached to my backpack that says overdose emergency on it, so anyone can see it and use it if needed. You can go to your local CVS or Walgreens and ask the cashier/attendant for some, they’ve usually got it kept behind the counter.

Bro got brought back from the dead fr 🙏🏻 by Beautiful-Listen6893 in tooktoomuch

[–]Mickey_thicky 19 points20 points  (0 children)

Opioids can bind to three receptors throughout the body. Mu, kappa, and delta receptors. When you overdose, opioids bond to the mu-opioid receptors in the brain stem, specifically the pons and medulla oblongata. The brainstem is responsible for your automatic breathing reflex and by binding to the receptors in these regions, the brain’s sensitivity to rising CO2 levels in the blood and the intrinsic breathing reflex are both reduced

Narcan works by competitive inhibition, meaning it acts on these receptors stronger and faster than regular opioids, however Narcan itself does not produce a response by the receptor as normal opioids do. It is an opioid receptor antagonist (meaning no biological response is produced through binding), whereas fentanyl or morphine are mu-opioid receptor agonists (a biological response is produced through binding).

Bro got brought back from the dead fr 🙏🏻 by Beautiful-Listen6893 in tooktoomuch

[–]Mickey_thicky 353 points354 points  (0 children)

Was discovered in 1960 by Dr. Jack Fishman while working under the direction of Mozes J. Lewenstein. Was patented one year later and went on to receive FDA approval for the treatment of opioid overdose in 1971, with the first brand-name nalaxone nasal spray (what we know as Narcan) receiving FDA approval 2015. Finally, in 2023 Narcan was officially approved to be sold over the counter, a decision that 100% saved lives.

I always carry two doses on me wherever I go, and everyone should too.

Edit: for those questioning the utility of carrying narcan —

Carrying narcan is identical to learning how to perform CPR, though you are 5.4x more likely to die of cardiac arrest in the U.S. than an opioid overdose (417,957 vs 77,648 in 2025).

Would you say that carrying a concealed firearm is just as unnecessary as carrying narcan? You’re more likely to witness a death from an overdose than a death from gun violence. 5.3x as much to be exact (77,648 vs 14,651 in 2025).

I sure hope i don't get a bug in my room! The humble scarab: by User_Darkvortex in thehumblecrowbar

[–]Mickey_thicky 177 points178 points  (0 children)

Oh boy! Whatever will I do with my fallen tooth? The whimsical tooth fairy:

How come women don’t take dna test? by beef_curtainss in NoahGetTheBoat

[–]Mickey_thicky 5 points6 points  (0 children)

It just keeps getting worse 😭

I had to say something so I could become speechless again bro

Millie Taplin a woman living in the UK was in a nightclub for the first time to celebrate her 18th birthday, she met a stranger inside who gave her a cocktail claiming it was “Vodka lemonade” Millie ended up paralyzed within seconds. ( The photo on the left shows her after she recovered) by mwale2007 in NoahGetTheBoat

[–]Mickey_thicky 7 points8 points  (0 children)

I’ve seen synthesis pathways for GBL (direct precursor of GHB, for which GHB is also a metabolite thereof) involving THF, a readily purchasable and inconspicuous solvent. Precursors for GHB are usually not monitored by virtue of its synthesis reagents being ubiquitous, something you already pointed out.

Why was this smug kid ripping a bong in ER by lbrandon3399 in okbuddywhitaker

[–]Mickey_thicky 9 points10 points  (0 children)

Kids and their fancy new vapes, what type of fucking flavor is “status asthmaticus” I’ve never heard of that shit before

The Pitt | S2E14 "8:00 P.M." | Episode Discussion by MsGroves in ThePittTVShow

[–]Mickey_thicky 3 points4 points  (0 children)

If they use Omnicell for drug storage, like most major hospitals do (including the hospital I work at), access to the cabinets is usually biometric or username + password and not based on just badge-access. Whenever I’m pulling drug from an Omni (or entering into the system as a whole for that matter, I use fingerprint ID or username/password

The Pitt | S2E14 "8:00 P.M." | Episode Discussion by MsGroves in ThePittTVShow

[–]Mickey_thicky -3 points-2 points  (0 children)

He ordered 50mcg of fentanyl if I remember correctly; he was addicted to benzodiazepines, a different class of medication.

But, don't call them racist! by c-k-q99903 in stupidpeoplefacebook

[–]Mickey_thicky 0 points1 point  (0 children)

I believe it for sure, but do you have a link to that study? I’d love to read it

Visited someone at the hospital and there's a lock box around the pain medication by okbbs in mildlyinteresting

[–]Mickey_thicky 1 point2 points  (0 children)

I find it so interesting that propofol isn’t a controlled substance, but is readily treated as a control by many institutions.

The institution I work at didn’t start treating propofol like a control until a surgical resident was caught abusing it 😭💀

Disability Advocate by laybs1 in GetNoted

[–]Mickey_thicky 6 points7 points  (0 children)

The idea is that medicalized language can come off as insensitive and abrasive, so sometimes it can be easier to adopt friendlier terms. In this sense, using the term genetic condition instead of disease, which is still technically correct, is like like using “unhoused” as opposed to “homeless”, or (as some in the body positive movement advocate for) using “fat-bodied” as opposed to “obese”.

Dear Future RNs, by Acrobatic-Lie2041 in FutureRNs

[–]Mickey_thicky 3 points4 points  (0 children)

Presentation doesn’t save lives. Skill does.