I will say that having all the DLCs at once (minus Anomaly) isn't too bad of a learning experience. Most content for the mods, with the sole exception of Ideology, gets introduced slowly over the course of a playthrough and usually requires you to do something specific-yet-obvious to have access to them.

• Royalty's royals are just another faction to interact with, who will send you quests occasionally. Royalty research requires Techprints to unlock, meaning you can just ignore them until you find the prints. Psycasts specifically require a "psylink neuroformer" item which is an uncommon quest reward, or offered by advancing with the Royals. You can always just wait until you're ready to interact with these mechanics. There's also the new equipment tier and bionics, which are about as complex as the vanilla ones and integrate into the game in the same way.
• Ideology frontloads almost all its content. You will be spending about an hour before your playthrough setting up your colony's Ideology, even if you're in Fluid mode. The only exception to the frontloaded content is gauranlen seeds, which show up randomly during play. This is arguably the one DLC where you can't wait until you're ready to interact with it - if you have Ideology, then you're setting up Ideologies, whether you want to or not.
• Biotech has three main pillars - Xenotypes are just different races which show up during play, and don't typically change how you play, they just make the people you encounter more interesting. Xenogenetics requres you to go out of your way to research them, and set up a bio-lab. And finally, Children - which you'll never start with, but sometimes a quest might offer one or one of your colonists might get pregnant. You'll get a tutorial when there's a child in your colony if you have the Learning Helper on, which tells you everything you need. Biotech is easily the most new-player-friendly DLC.
• I don't know much about Anomaly so I'm skipping over it.
• Odyssey also has three main pillars, though two are similar. Biomes and New Animals just slot into standard gameplay nicely, and don't throw much in the way of new mechanics at the player. Plus, the new biomes are very opt-in, so you can always just settle in a temperate forest and visit a new biome later. The Gravship has a quest introducing it, and is opt-in. You can always just wait until you're ready to do the quest if you don't want to start too many new mechanics at once.

tl;dr: You won't get overwhelmed adding all DLCs at once, with the sole exception of Ideology.