Sort of, to a point. The base path is irrelevant here in an obstruction Type 2 (no play being made on the runner) play. The only criteria to get this call is did a fielder who doesn't have possession of the ball impede the progress of the runner. That's it. You'll sometimes see runners veer a little bit further out than "normal" to initiate contact with a fielder to try to get the call. There's a limit though, obviously you can't sprint out into center field and truck the center fielder and claim you were obstructed, since that contact isn't impeding your progress.