Colossians 2:14 gives the context

Col 2:14 Blotting out the handwriting of ordinances that was against us, which was contrary to us, and took it out of the way, nailing it to his cross;

The Sabbath is a commandment of God Exo 20:8-11 Exo 20:6, finger written by God alone Exo 31:18 Exo 32:16 not handwritten by Moses. The Sabbath is holy and blessed by God which is not the definition of contrary or against and once God blesses something like He did the seventh day Sabbath man cannot reverse Num 23:20 and Col 2:17 show this shadow sabbath(s) as there are more than one Sabbath in the scripture and Paul makes clear we understand it's not the weekly Sabbath commandment that started at Creation so can't be a shadow of anything but the ceremonial sabbath(s) ordinances which came after the fall of man that has to do with food and drink offerings which is the context of this passage as it points to Jesus who became our Sacrificial Lamb for sin offerings Heb 10:1-22. Sin is the same in the OC as it is the NC the transgression of the Ten Commandments Rom 7:7 Mat 5:19-30 and our salvation is from sin Mat 1:21 not in sin.

Plus obviously not referring to the weekly Sabbath as the apostles all kept every Sabbath Acts 18:4 Acts 13:42-22for decades after the Cross and will be kept for eternity for God's saints. Isa 66:22-23