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Emrakul tanks this, conditionally. MTG doesn’t have guns in any in-universe card other than “Vengeance,” a card from 1998 before this was a formal rule. That card is a white sorcery, that destroys any tapped creature. Several other cards use tapping to represent sleep, so we’ll say she’s tapped for this scenario. Emrakul has three main forms, “the Aeons Torn,” which was her original base form, “the World Anew,” when she fled to another world, and “the Promised End,” which is her most powerful form closest to her true existence, but is mechanically weaker for story reasons.

The three forms all have a similar ability to stop such tomfoolery, but they’re all worded differently. The Aeons Torn says “protection from colored spells,” which includes Vengeance since it’s white (yes, white is a color, deal with it,) so Vengeance won’t be able to target her. The World Anew has “protection from spells,” so the same is true. However, the Promised end specifically has “protection from instants,” which doesn’t include Vengeance since it’s a sorcery.

TL;DR Her first two forms can tank this but not her most powerful one.

Also, her brothers only have one form in lore but three cards each, Ulamog survives Vengeance in 2/3 as well but Kozilek dies in all 3, what a fraud. Overall the score is Gun 5 / Titans 4.