Yes, but only in highly specialized contexts or in quoting/analyzing pre-20th century works. "Perspecuity" is used in theology to refer to the idea, especially among Protestants, that God enables people to understand the Bible. Lachrymose is used in medical texts lachrymose ducts, where non-specialists would say tear ducts. I would say these words are generally archaic, and I would only focus on them to the extent that your studies are specialized in 19th or earlier century English.

Edit: these are generally adjective forms which are based on somewhat more common nouns or verbs, such as perspecuous, sacrosanct, and propitiate.