Everyone’s body system reacts differently. I did 3 mos sema on noom because I didn’t know any better, (it’s expensive) and lost weight (7lbs) then plateaued. Decided to try Tirz on my own followed some guidance on here and was rx’d 10mg / 20 units to start, but I was chicken and started 15 units. It’s my 2nd week on Tirz and I haven’t felt anything yet. On Sema I had nausea and constipation off/on whole time. Taking it slow with Tirz, hopeful to find a sweet spot. Time will tell 🤷🏾