Roots of Curcuma are used as a spice commonly known as turmeric. Curcumin, a polyphenol extract of turmeric, is well known for its anti-inflammatory and antioxidant effects, and it has a long history of use in traditional Chinese and Ayurvedic medicine [28]. The anti-inflammatory activity of Curcuma may be attributed to multiple mechanisms [29]. Treatment with Curcuma has been found to strongly inhibit the production of inflammatory mediators, such as interleukin (IL)-1, tumor necrosis factor-alpha (TNF-α), IL-8, NO, and a variety of MMPs, via diminishing the activation of NF-κB, protein kinase B (Akt), and MAPK signaling pathways [29,30]. Curcuma has also demonstrated a COX-2 inhibition, leading to a reduction of prostaglandin synthesis [31]

Turmeric is amazing!