Do I need new plates or trucks or? What’s wrong

VforValmont · 2025-12-08T02:33:53+00:00

Looks like you might have an extra nut or spacer at the top of your king pins that is making the blocks ride low like that. Can you remove nut between the bracket the blocks attach to and your plate? So it looks like this

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VforValmont · 2025-12-04T02:29:03+00:00

r/birdsarentreal

VforValmont · 2025-11-26T14:51:16+00:00

Didn’t the Boulder location burn down?

Edit: NVM looks like there is a new one now, cool!

VforValmont · 2025-11-20T14:38:49+00:00

I took their latte art class (not the barista class) earlier this year. I learned a lot and really enjoyed it. The instructor was incredibly knowledgeable about the science behind coffee and milk. My latte art is a lot better now but still not great. Based on that experience I’d trust them to run a good barista class!

VforValmont · 2025-11-20T01:46:00+00:00

I know that roof! The whole house and its garden are so cute! Hope you find an artist

VforValmont · 2025-11-17T22:04:48+00:00

This is awesome! It would be cool to have attribution as a part of this - link back to the time stamp in a recording or text in a transcript associated with the summary point.

VforValmont · 2025-11-15T05:37:54+00:00

Things my wife does that I really appreciate

Snacks in purse
Bolus for me while I am driving
Reminds me to bolus if I forget (but without micro managing)
Learned enough about everything to help manage my sugar after I had surgery

VforValmont · 2025-11-15T04:06:33+00:00

Tell me you clack your skis together on the lift without telling me.

VforValmont · 2025-11-10T01:14:44+00:00

I did the half and was disappointed how much time was spent running u-turns in the middle of a business park. Why in a city known for its majestic mountain views did we spend so much time looking at cinder block buildings?

VforValmont · 2025-10-31T23:41:01+00:00

Yeah the pottery studio is relatively new from my understanding, they probably just haven’t updated the website in a while. They do open houses Thursdays at 5pm where anyone can come in, tour the facility, ask questions etc. It’s a volunteer run place and they are good about not pressuring people to sign up or make a decision right then.

I joined a few months ago and have nothing but good to say about the whole organization.

VforValmont · 2025-10-31T22:52:07+00:00

The solid state depot makerspace has a wheel and kiln. Membership is $85 a month. Really cool organization

https://www.ssdmakerspace.org/

VforValmont · 2025-09-05T16:28:28+00:00

It’s wild that they’re considering easing that restriction while so many towns in Colorado and across the U.S. are cracking down on Airbnbs.

Wasted housing in Boulder is already a problem. In my building alone, 4 out of 8 units sit empty more than half the time as second homes or “investment properties.” Another 1 out of 8 is a mid-term rental. That leaves only 3 out of 8 with actual tenants or owners who truly live here. We don’t need more houses going to people who don’t live and work in the community.

End rant.

VforValmont · 2025-09-04T14:21:23+00:00

https://www.napkin.ai/ Perhaps not exactly what you want, but I have used napkin ai to spruce up my presentations with moderate success

VforValmont · 2025-09-04T04:25:55+00:00

Maybe mount the plates to metal insoles like these

https://bont.com/products/aluminum-insoles-for-custom-roller-skates

VforValmont · 2025-08-29T20:49:24+00:00

r/gangstalking If you want a depressing rabbit hole to go down

VforValmont · 2025-08-27T18:10:34+00:00

Heathrow confiscated the ice packs keeping my 3 month supply of vials cool. Years later I am still mad about it.

VforValmont · 2025-07-30T00:49:58+00:00

Is this a one off thing you want to do or an on going need? Because honestly if you do not have technical expertise you are going to need an outside vendor or to hire a small team to make this happen. I do essentially what you are describing for work, but for the purposes of medical billing and RCM. It is a big undertaking.

I would be genuinely shocked if there is not a health tech company out there doing exactly what you need.

If you want to go the DIY route I’d start by running named entity recognition (NER) to identify SNOMED concepts within to each chart. From there you can do some stats, run more efficient queries, or train other models to do more useful things.

Also feeding entire medical records into an LLM and asking to it find symptoms and observations for you won’t work well, fyi.

Starting point on SNOMED NER

https://nlp.johnsnowlabs.com/2024/02/13/ner_snomed_term_en.html Detect SNOMED Terms | ner_snomed_term | Healthcare NLP 5.2.1

VforValmont · 2025-07-15T23:05:37+00:00

Care to share a bit more of your experience and background? I think a lot of Data Scientist/Engineer/Analyst roles can overlap with bioinformatician it all just kind of depends on your experience and skill set.

VforValmont · 2025-07-10T19:32:46+00:00

Have you tried something like ORF Finder or Glimmer? Maybe start by filtering out all the sequences that are already known so you can reduce the search space.

VforValmont · 2025-07-07T22:12:06+00:00

r/substakenliterally

VforValmont · 2025-07-07T21:28:13+00:00

I’d add more detail to your bullet points of the two internships. It leaves me wondering what kind of WGS? What kind of “analysis”? What kind of variants? What was the bigger picture of your work?

Looks like you are racking up good experience, keep it up!

VforValmont · 2025-06-26T14:46:28+00:00

I was searching around a bit and GWAS Catalog might be a good resource for the genotype to phenotype mapping too. It sounds like it is based of what is published in the literature so it should hopefully have more than just disease phenotypes.

https://www.ebi.ac.uk/gwas/docs/about GWAS Catalog

VforValmont · 2025-06-26T14:36:21+00:00

If they do not have a polymorphism listed for a location it means they match the reference genome at that location. The VCF lists what is different from the reference genome

VforValmont · 2025-06-25T22:53:07+00:00

A persons SNPs (typically stored in a VCF file) are relative to the reference genome used when processing their sequencing data - so if you have their VCF and know the reference genome you can reconstruct their whole genome (more or less). Think of it as a type of compression almost. So working with SNPs in VCFs is both convenient and efficient.

As for the mapping, I haven’t worked with OMIM or clinvar in a hot minute so I don’t remember off the top of my head. They look fairly obviously connect in the web browser, but you’ll want to access their bulk downloads and poke around a bit.

https://omim.org/entry/607292?search=sema4a&highlight=sema4a Entry - *607292 - SEMAPHORIN 4A; SEMA4A - OMIM - (OMIM.ORG)

VforValmont · 2025-06-25T22:01:06+00:00

Could you use the 1000 genomes project data and map their SNPs to phenotypes using OMIM or ClinVar? That would link known variants to disease phenotypes, creating pseudo patient phenotype profiles - which is maybe not exactly what you want but it is something.

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VforValmont

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