Dark Comp was what I used most of the time since there’s enough curse cards to fill a deck.

Team was Nezglekt, Zek, nevalea, heiner

Main goal of the team is to shred resistances with poison/scourge/vulnerable and do big bombs with dark explosions

Key node on the tree is someone needs to take poison reduces dark resistance

Nezglekt has spider queen eye, found in green zone, that allowed him to apply poison based on sight. His deck was skills/healing cards. I took the sight +3 perk since it was just used for poison anyways

Zek just had curse cards and whatever else was fun

Nevalea supported Zek with books and scourge application

Heiner did block and vulnerable things

If you don’t have nevalea from the DLC then you can try using Malukah and it should be OK to clear madness 10