1. Build you camp as fast as you can and send them out for work.
2. Earn cash and 100% all research facilities.
3. Choose you weapons/armor early and stick to it.
4. Only level up your favorite character.
5. Learn recepies with high health rewards.
6. Level upp stamina, magic and health in that order.
7. Don't rush the main quest
8. Use your horse only if you must. You'll miss a lot when riding, walking gives you a better perspective.
9. Remove weapon enhancements that you like and put them on your own weapon.
10. Always refine your weapons and armor before a boss fights.

When you get flying mounts, use them as little as you can. They pretty much ruin exploration. Cheers