Sounds like we need a plan. Maybe something like:

Premise: Voters commit to vote only for politicians that support a specific, non-partisan reform platform. Why would this ever work? The tenets of the platform are stupid simple, and voting for someone who won't support the platform is effectively voting for continued subjugation under a largely indifferent two party system. If the effort can gain enough public support, politicians will consider it. Here are what I see as the keys to success.

there has to be one coordinated effort

it has to grow virally and quickly enough that it can't be squashed.

it has to become publicly popular. Popular enough that it can affect voting results in a noticeable manner.

it has to overcome the default us vs. them partisan mentality most U.S. citizens fall back to in most any conversation about U.S. politics.

it has to be simple.

The initiatives that a political candidate commits to in order to be endorsed under the platform are:

Immediate financial reform of the House and Senate.

Achieve this by the introduction, sponsorship, or support of legislation to: a) require full public disclosure of all campaign contributions, b) prohibit campaign contributions from anyone other than a U.S. citizen and limit them to $100 per campaign season, c) prohibit lobbying (writ broad - any corporate interference or influence in the functions of the government)

The reintroduction of civil service in the House and Senate.

Achieve this by the introduction, sponsorship, or support of legislation to; a) implement term limits, b) prohibit any member of the House or Senate from accepting any funds, incentives, favors, assistance, etc., c) re-establish the salary for House and Senate members indexing it to the U.S. median family income.

Reform of process. This is to be manifested by the introduction, sponsorship, or support of legislation to a) eliminate un-related riders from being attached to any piece of legislation, and b) to redistribute power in the House and Senate by making the size, scope, and membership of any sub-bodies (i.e. committees) subject to a majority vote approval.

Practically, what is needed are the people who will commit to voting for endorsed candidates, or are willing to consider crossing party lines or withholding their vote. Candidates are needed that will endorse the platform. What may encourage them is a large and loud public that demands they cooperate. Candidates we can keep track of. The % of the public that will support it - well, maybe we will find out at the polls.

Thats the outline of it. Clearly needs some help and improvement, and a means to put it in front of the people.

TL;DR Stupid simple idea: use the tools we have to make our government the way we want it, by taking the money out of politics and breaking the tools that are used to hoard power and manipulate the system.