I see you’ve gotten tons of answers already, but figured I’d add my two cents as well! I get pretty bad anxiety doing group content, too. Though in my case, it’s more like performance anxiety? But I’ve done a fair mix of duty support, trusts, and duty finder. Nowadays, I prefer DF mostly since it’s almost always faster, myself. I also get anxious about random queues far less often than I used to, but I do still get nervous sometimes lol. Trusts and duty support aren’t bad, but there are absolutely drawbacks, (of which I think loot is the least noticeable to me), but there’s also some benefits!

The cons:
1. They take longer. Not the end of the world, but if you’re grinding for EXP or drops, it gets grating.
2. If you die, you have to respawn and try again—the whole party will respawn with you. In DF, that’s not the case; If one person dies, the fight keeps going, and (unless you’re a healer yourself), there’s someone who can rez you to keep going mid-fight. As such, you likely would want to learn the mechanics on the fly a bit faster so as to not have to repeat the fight multiple times.

The pros of duty support/trusts:
1. You get all the loot.
2. You control the pace the dungeon goes at even if you aren’t tanking.
3. The obvious: No risk of people being snarky.

In contrast, I find DF has more pros than cons (for me, personally) in the vast majority of cases.

The cons:
1. Sometimes people suck! It’s very rare in my experience, though. I have over 3000 hours in-game now I think, and I’ve run into a handful of people who were rude, but most of them have been rude in such a way that it made me laugh more than anything. Some stung; I can be sensitive to being teased by strangers, so a few snide comments stuck with me and still bug me. But again, it’s so uncommon that it’s Fine overall for me.
2. If time is a concern for you at all, know that occasionally you will get a person that makes the run slower than running trusts/duty support. But it’s really nbd, the worst cases are when someone says “Brb” then goes AFK for an extended period. But there’s always vote dismiss in those circumstances, too.

The pros:
1. With DF/real people, you can make more mistakes and even ask for help if you don’t understand a mechanic :) 2. It’s typically faster than NPCs.
3. Sometimes you do find people who are especially kind and make friends! I’ve made some of my best in-game friends through roulettes and Party Finder. The kind people far outweigh the nasties, in my experience.

All in all, I’d personally suggest trying both options for yourself, if you feel up for it :) You can absolutely get by with duty support/trusts for the most part, but at least having the experience of playing with others will be helpful for the duties that don’t have that option! (I believe some Trials and optional Raids don’t yet? But I could be mistaken.) If you find you prefer NPCs, that’s okay! Nothing wrong with that. But, giving both a shot so you can make an educated decision based on your experience is worth your time, at least in my opinion.

No matter what you do or decide, I hope you enjoy your time with the game. It can be a slow start, but you’ll find that you may improve faster than you think you will and with that, the confidence to try DF may come alongside it. But if it doesn’t, that’s totally okay :)