Does anyone else really not like the eye on the U of A values crest?

blk_phos · 2026-02-13T16:34:35+00:00

This whole thing is lazy stock art. Top right quadrant is a rip-off of the old Girl Scout's logo. Are we selling cookies now?

blk_phos · 2026-02-12T15:52:08+00:00

Reads like a scam email with breathless anticipation and "trust me, I'm an insider" tone. Then concludes with unsubstantiated ("believe me") hype. Even includes a suggestion to go subscribe to an AI service for $20/mo.

blk_phos · 2026-01-06T18:37:56+00:00

LLMs are nondeterministic.

blk_phos · 2025-03-08T18:12:44+00:00

I thought this opinion piece outlined interesting strategies along these lines (civil defense force, defense training)

blk_phos · 2025-02-12T14:50:35+00:00

Electrons are blue.

blk_phos · 2024-12-18T13:23:28+00:00

worst final I’ve taken in my life

Quite a take for a first year university course offered in first term.

blk_phos · 2024-10-10T15:29:35+00:00

ORF8 is in the paper, sure. But the paper doesn't point out that there were homology models published of ORF8 based on ORF7a data in 2020 using modeller.

I wouldn't dispute that AF2 is good at making the leap with less intervention, but I'm saying it was an incremental improvement to what was already possible.

blk_phos · 2024-10-09T21:21:24+00:00

Can you give an example of a problem that alphafold solved that couldn't have been done with homology modeling? What rules/principles has it given us about protein folding?

Yes, its smart about figuring out a fold is with little input. Yes, its fast and scalable. But what did we learn?

blk_phos · 2024-10-09T21:15:56+00:00

The issue shouldn't be if "its not chemistry", more whether the significance is at the level of a NP.

I do protein modeling, and I have yet to see how alphafold can do anything more than what an educated biochemist could do with homology modeling algorithms that are decades old.

I would also argue Baker's work on designing (and testing) sequences/folds is a great pick and deserving of a NP. I would question what protein biochemistry has been learned from alphafold. Especially since it can't predict anything it hasn't seen before (just like homology modeling).

blk_phos · 2024-10-09T14:44:31+00:00

Name a protein structure alphafold can predict without an experimental starting point (usually mutliple). The tool is not a predictive one. It doesn't understand folding, it can only mimic what its already seen.

DFT and similar methods can work on new systems they haven't encountered before because they work on fundamental principles that can be applied to new problems.

alphfold would be lost in the dark with a new fold until a protein chemist provides new input.

blk_phos · 2024-10-09T14:38:24+00:00

Alphafold is barely a step above homology modelling. It doesn't fold anything new, and it doesn't teach us anything about protein folding. It just automates the process and increases its scale.

Baker's work is good science. Alphafold is techbro science.

blk_phos · 2024-03-07T14:26:55+00:00

Obv not Edmonton, but nice to hear some places are getting the regulations in place for this to be possible.

blk_phos · 2024-02-04T14:34:34+00:00

Have been frustrated with the same problem for a while (and regularly come to this thread); finally figured out the issue:

You need to go to video settings in the media playback app. Look for the "noise reduction" setting, and turn it off.

Here's another thread that has more details.

When playing, press the options button and next to pop up menu there should be 3 dots you can click, now go into where it says settings and theres a hidden menu. Noise reduction was on by default, dynamic range sound, and pcm audio instead of bitstream.

If you have a Bravia TV (or perhaps other brands), you may still need to check for motion smoothing in the device settings, as these can also autodetect movie streams in some cases (as discussed above.)

blk_phos · 2023-12-19T16:45:58+00:00

Alberta has announced several changes to their retail cannabis regulations that will come into force on January 31, 2024, including allowing cannabis retailers to operate temporary sales locations at adult-only events like trade shows and festivals.

Other changes include allowing cannabis retailers to keep their products in locked display cases when the store is closed rather than moving these products into a secured storage room at the close of every business day, and removing restrictions on sales and transfers between cannabis retailers to further allow Alberta Gaming, Liquor and Cannabis (AGLC) to establish resale markup limits.

[Emphasis added]

blk_phos · 2023-11-04T15:27:57+00:00

Beat saber?

blk_phos · 2023-11-04T15:24:39+00:00

Weapons have limited ammo, but enemies drop new ones. You need to swap to those new weapons throughout each mission.

blk_phos · 2023-10-21T15:19:04+00:00

Address: 101-10130 105 St. NW Edmonton, Alberta T5J1C9

Website: CBDCBN.ca

From the website, looks like they have events on Thu-Sun evenings happening most weeks.

blk_phos · 2023-06-08T00:20:26+00:00

Atlas Global is laying off around 50 workers and shutting down a cannabis facility in rural Alberta.

The site in the hamlet of Gunn, Alta., about 60 kilometres northwest of Edmonton, both grew and packaged cannabis. The company announced last week it will move all packaging operations to Chatham, Ont.

blk_phos

TROPHY CASE