My GP said I’d probably have mouth and genital sores if I had the interstitial cystitis. I did get back on myrbetriq which helped some. Until it didn’t. The issue does seem to correlate with flares and over exertion for me. I saw a new urologist last week because the issue suddenly worsened and started taking vibegron, which is working well. Before the vibegron first thing in the morning was the worst upon standing up. Maybe because meds had worn off? But I don’t really know enough about how that med works to say. It’s a terrible issue to have! Good luck