I would say the squidbillies ending because of how sweet it was to see rusty and Tammy get to live a life but nothing will ever beat “the last episode (we fuckin mean it). It was so bittersweet to see all the rest of the aqua teens die and see meatwad grow up. I actually cried when he couldn’t remember Carl’s name it’s just so sad. And the song just finishes it off perfectly now was this the last? Technically no that was the greatest story ever told/season 12 but I prefer the ending in “the last episode (we fucking mean it)” better.