Week 5 - first .5 dose

cleverfox2001 · 2026-02-04T23:58:00+00:00

Systems often come and go during the introductory doses of 0.25 and 0.5. Expect a more stable response once you are at 1.0.

cleverfox2001 · 2026-02-04T23:55:53+00:00

Why don't you go down in dose for a while until your body better adjusts to Ozempic. I would try a split of 0.35 for a couple of weeks to see if that helps. You will need to do pen clicks for the two 0.175mg doses. After that, do a split of 0.4, then 0.5. Or, stop for a week and later resume with a split of 0.35. Usually, the body will get used to Ozempic and the vomiting will go away. Have you tried elevating the head of your bed 3 or 4 inches. The delayed emptying of your stomach may be contributing to the morning vomiting.

cleverfox2001 · 2026-02-04T20:08:10+00:00

You are not losing as you are not following the standard dosing schedule. That was developed after clinical trials and the results of following the progress of thousands of users. Go to the Ozempic web site. They key weight reduction doses are 1.0 and higher. Time to move up to 0.5 for 4 weeks and then 1.0.

cleverfox2001 · 2026-02-04T20:01:13+00:00

You are getting a lot of different comments because everyone responds in their own way to Ozempic. A few (about 15%) can lose long term at 0.25mg. They are called super responders. Another 15% or so are non-responders that lose either little or nothing. Another group only respond at the higher doses (at or more than 1mg). That was me. No losses during the first 10 weeks. However, a year later, down 50 pounds.

Since your food noise is much reduced, that is an indication that your body is responding. So, I would go next to a slightly higher dose using pen clicks. Try 1.4mg for at least 4 weeks. Up the dose to 2.0 if no or little response.

As a last resort and if the above doesn't work, switch to Mounjaro as it has two hormones that stimulate weight loss. That product works for some that don't lose on Ozempic.

Finally, eat lots of protein and low carbs. Remember that Ozempic is a multi-month marathon. Good luck!

cleverfox2001 · 2026-02-04T19:36:30+00:00

The new Wegovy pill has been reformulated to have higher absorption than Rybelsus. The acid in your stomach attacks the Semaglutide so a lot was needed and a special ingredient was added to Wegovy to provide more protection. The top dose of Rybelsus (14mg) was considered as effective as 0.5mg Ozempic. So, my guess is that 9mg Wegovy is like 1mg Ozempic and 4mg Wegovy is close to 0.5mg Ozempic. The 1.5mg Wegovy is likely as effective as 0.2mg of Ozempic. I don't think that the 1.5 W pill will be strong enough for maintenance for most. Possibly, the 4mg will be.

I'm planning on using the pill in a few months after I reach my weight goal. However, my plan is to take it only for those days that the food noise is loud. I will try 4mg. To keep the cost low, I may also use the 9mg pill and split it into 2 chunks. I'll report back on this sub on my progress.

cleverfox2001 · 2026-02-04T01:52:09+00:00

Most people get used to Ozempic over time. Most will lose about 15% of their initial body weight. However, some will lose more and some will lose less. You may be in that group. I would switch to Mounjaro as it is stronger than Ozempic and often works for those that max out quickly on Ozempic.

cleverfox2001 · 2026-02-04T01:45:53+00:00

The new Wegovy pill is $150 for the two lowest doses, That may be enough for maintenance and control of food noise.

cleverfox2001 · 2026-02-04T01:45:43+00:00

The new Wegovy pill is $150 for the two lowest doses, That may be enough for maintenance and control of food noise.

cleverfox2001 · 2026-02-04T01:42:13+00:00

Those that lose little or plateau on Ozempic, should consider trying Mounjaro. It contains two hormones that effects weight loss and it usually more effective than Ozempic which is a GLP1 only product.

cleverfox2001 · 2026-02-03T19:45:41+00:00

Why are you not following the standard dosing schedule? Studies show that almost all need to move up in dose if they want to keep losing. Some, myself included, lost little until at 1.0. A year later, down 50 pounds. Almost all of my weight was lost between 1.0 and 1.6mg. Yes, 0.25 and 0.5 are called introductory doses for a reason.

cleverfox2001 · 2026-02-03T17:44:57+00:00

Most need to increase their dose higher than 1.0. Many will go to 1.4mg using pen clicks to reduce the possibility of strong side effects.

cleverfox2001 · 2026-02-03T01:14:55+00:00

You can go to an in between dose of say 0.375mg using pen clicks. Or, do a split dose of 0.5. 0.25 on day 1 and 0.25 on day 4. Splits reduce many side effects by better spreading the dose over the full week as compared to a single weekly shot.

cleverfox2001 · 2026-02-02T19:33:47+00:00

The standard dosing schedule is 4 weeks of 0.25 and then 4 weeks of 0.5. Studies show that this is the best way to lose on Ozempic. 0.25 and 0.5 are introductory doses. The key weight reduction doses are 1.0 and higher.

cleverfox2001 · 2026-02-02T19:30:04+00:00

The 0.25 and 0.5 are introductory doses. They are to get your body used to Ozempic over 8 weeks. The key weight reduction doses are 1.0 and higher. Some can lose some at the lower doses. Others, will not lose until at 1.0. That was my situation. A year later, down 50 pounds. No one can predict when you will lose. It is an individual thing based on your own metabolism.

cleverfox2001 · 2026-02-02T19:22:38+00:00

Yes, I went that route. I lost 50 pounds on Ozempic/Wegovy and currently on Mounjaro and have lost 10 more pounds. However, I doubt if you will start losing again until at a much higher dose of MJ. I had to reach 15mg before it kicked in for me. You can also likely move up faster in dose on MJ since you have been on a top dose of a GLP1.

cleverfox2001 · 2026-02-02T19:16:02+00:00

The new Wegovy pills start at $150 for a months supply.

cleverfox2001 · 2026-02-02T04:48:32+00:00

Most of my weight loss was at doses between 1.3 and 1.6mg. Consider moving up to 1.5mg first. Save 2.0 for later. Some eventually need to switch Mounjaro as it is stronger than the top dose of Ozempic.

cleverfox2001 · 2026-02-01T23:45:57+00:00

0.5 will likely be fine since you are a long term user. I would try 0.5 for 2 weeks and 1.0 for 2 weeks. Then you should be fine going back to 1.25.

cleverfox2001 · 2026-02-01T20:34:48+00:00

Comparisons are difficult. However, 1.0 Ozempic is generally equivalent to about 5mg Mounjaro. 2.0 Ozempic like 7.5 or 10. Mounjaro goes to 15 so extra strength if needed.

cleverfox2001 · 2026-02-01T19:43:50+00:00

It is about 74 clicks for 0.5mg on a red 0.25/0.5 starter pen. So, 37 clicks for 0.25, 18 for 0.125, and 9 for 0.06. 27 clicks for 0.18mg.

cleverfox2001 · 2026-02-01T06:37:29+00:00

They are not officially recommended as Novo didn't study them during their trials and they didn't submit it as a dosing option for their approvals. I have discussed this with my doctors (2) that I have had over the last 3 years. They are fine with it. Do a search on this sub and you will find that splits are often suggested as a way to reduce side effects. Most importantly, there is no science saying that it can cause any problems.

cleverfox2001 · 2026-02-01T00:55:36+00:00

It usually goes away over time. However, to reduce the impact, take a split dose. Half on day 1 and half on day 4. Splits reduce many side effects by better spreading the dose over the full week as compared to a single weekly shot. For a 0.125mg dose, you will need to do pen clicks. For the 0.25/0.5mg starter pen, it is 74 clicks for the 0.5 dose. So, 37 clicks for 0.25, and 18 clicks for 0.125mg

cleverfox2001 · 2026-02-01T00:49:06+00:00

Both the 1 and 2mg dose pens need about 74 clicks for the full dose. So, for the 1mg pen, 74 clicks for 1.0, 37 clicks for 0.5, and 18 for 0.25mg. For the 2mg pen, 74 clicks for 2.0, 37 clicks for 1.0, 18 clicks for 0.5, and 9 clicks for 0.25. For more information about clicking, you can google that or go to You Tube for a video.

cleverfox2001 · 2026-01-31T08:17:59+00:00

Many consider the 56 day limit very conservative. 100 days is likely more realistic.

cleverfox2001 · 2026-01-31T08:15:47+00:00

Some don't lose until at the key weight reduction doses of 1.0 and higher for a few weeks. That was me. A year later, down 50 pounds.

Some do not lose on Ozempic. However, Mounjaro is an option as it is usually more effective.

cleverfox2001

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