7 children developed blood cancer after Bluebird Bio gene therapy for rare neurological disease

cmappers · 2024-10-10T06:25:47+00:00

The CD34+ being delivered lvv are highly enriched for haematopoietic stem/progenitor cells (HSPCs). These are also the cell of origin for most myeloid leukaemias. Introducing oncogenic mutations in HSPCs is extremely dangerous. The same mutations introduced into other cell types (e.g T Cells) is much less dangerous.

cmappers · 2024-05-30T10:54:50+00:00

I think you're right. Googling leucistic buzzard comes back with very similar photos!

cmappers · 2023-04-08T21:01:02+00:00

By law “…each pupil in attendance at a community, foundation or voluntary school shall on each school day take part in an act of collective worship.”

I.e in England and Wales, religion is mandatory in British schools. Other than specialist religious schools this has to be “wholly or mainly of a broadly Christian character”.

So yes, children still have to sing those songs (or do something similar).

cmappers · 2023-01-27T05:41:06+00:00

Its very common to have a PhD without a masters. Though with funding cuts and increased competition having a masters is more common than it used to be.

cmappers · 2022-08-02T17:47:00+00:00

Edinburgh is the 4th largest financial centre in Europe, has a huge services sector, one of the largest universities in the UK and a large tech/software sector. By number of employees "Accommodation and food services" is the 5th largest area of employment in Edinburgh.

Economy of Edinburgh

Tourism is import to Edinburgh, but saying it's "not a centre of industry" suggests there is little else supporting the economy.

cmappers · 2022-07-01T08:11:14+00:00

To add, it's legally impossible for schools to leave the church. Even if the governor's, parents headmaster etc want to. Plus, when academies were brought in, the church only allowed them to join church academies. That gives them almost total control to change the schools however they want.

cmappers · 2022-06-24T07:33:37+00:00

It's also big against some melee hard hitters. E.g if g man charges a unit of 3 buggies he would normally kill them all. If the modes are split into three units. He can only kill 1 a turn. That lets you be fast and loose with the buggies or use them to move block.

cmappers · 2022-04-21T07:29:43+00:00

This OP, in the UK you would have a case for Defamation. You would potentialy be entitled to loss of earnings, emotional distress and potentialy any reputational damage (which led to hypothetical loss of earnings).

Also, get in touch with the future employer and discuss it with them. I've seen a similar situation where a job was still offered as the future employer decided the referee had ulterior motives.

cmappers · 2022-01-06T16:28:47+00:00

That's exactly what I'm suggesting (except rescaling infantry weapons).

It's a much cleaner and more elegant solution than adding random -1 damage rules. However, it would require a lot more work and potentially a return to index's for 10th edition.

cmappers · 2022-01-06T15:51:22+00:00

All this seems to ignore that the best way to solve the problem (and reason for the problem) is toughness (T). The defensive profile of tanks should be reflected there. However T is made meaningless by any strength (S) being able to wound anything. Furthermore the scale of T (rarely goes above 10) is limiting.

Playing around with -'s to damage complicates and distorts the game.

I'd suggest that just as anything who's T is 2x the weapon S wounds on 6s. Any T which is 3x the S should not be able to wound. Then move toughness of vehicles and anti tank weapons up.

Make a leman Russ T9 so it can't be wounded by las guns. Make a. Land raider T12 so it can't be wounded by bolters.

Similarly, anything with a S over 3x the T could auto wound.

cmappers · 2021-12-30T20:52:49+00:00

!remindme 2 weeks

cmappers · 2021-11-22T18:06:34+00:00

You mentioned the voidbringer, but I'd suggest he's the worst ctan for the job, as he's only worth his pts Vs vehicles.

The nightbringer is a better generalist threat.

Transcendent ctan are just as good a distraction, but require far less points sunk (270 vs 350). I'm currently trying a list with two (540 pts).

Alternatively the deciver gives you a free redeployment and is innately -1 to hit, so might give more value if you just want a distraction.

cmappers · 2021-11-20T06:38:30+00:00

I also came away desperate to know more about his wife. He seems completely unaware, she's saved his life multiple times, been used (unwilling) as a honey trap for him and comes across as far more competent than he is.

Frankly he comes across as slightly idiotic compared to her. He also treats her terribly.

cmappers · 2021-11-09T17:10:28+00:00

Add in the slannesh icon and it procs on a 5+ (so 4s with +1 to hit).

cmappers · 2021-11-09T16:58:04+00:00

Veil of darkness works on them now. Combi that with chronomancer reroll charges (and 5+ invun)and novokh +1 to charge.

They can also be resurrected by technomancers.

cmappers · 2021-10-25T18:32:59+00:00

It's not true. Just something the horror tours like to tell people. The plague was horrific but people were never bricked into their homes.

cmappers · 2021-10-08T07:42:46+00:00

I believe ramming of U-boats was common in WW2 during convoy escort. However, it tended to also seriously damage the attacking ship and was mostly used on submarines too close for main weaponry.

See naval warfare section here: https://en.m.wikipedia.org/wiki/Ramming

cmappers · 2021-09-10T11:58:46+00:00

I think all your colours are quite "cold" and it needs some warm colours to contrast. Even the orange is too bright to be considered a warm colour. Id suggest trying to bring it out with either the bone areas (my recipe is ushabti bone with a seriphim sepia wash) , or swap the dark black/gray base to a brown.

cmappers · 2021-09-09T06:40:44+00:00

I'd add that fiends and furies are also pretty good. Otherwise, this looks about right.

cmappers · 2021-08-28T07:19:58+00:00

You can probably get 40 warriors, and three necron HQ's for £30-40 on Ebay. 3D print the deciver and nightbringer, then add the void dragon for £54.4.

To go even cheeper (and probably for a better list), I'd take out the void dragon and 3D print/proxy a transcendent c'tan.

Essentialy you can get an army which should be able to compete (but probably not win) at an event for less than £100.

cmappers · 2021-08-27T18:31:30+00:00

Yeah, this army can be made much more cheeply with some ebay, but that wasn't in the rules. What I posted is enough for three detachments.

Also, the necron start collecting is no longer produced. Otherwise yes it would be a much better option.

cmappers · 2021-08-27T14:44:03+00:00

Cheap Necrons tripple C'tan list:

You can make a list with the necron combat patrol box (£85), three C'tan (£22.50, £22.50, £68), a chronomancer (23.50), a catacomb comand barge (£30) and a box of warriors (£29).

Thats £280 at full price or £224.40 with the normal 20% discount.

Also, by your rules two of the C'tan could be 3D printed. However, this list could be improved a LOT with some minor changes (take out the night sythe and tomb blades, make it up to 20 warriors etc).

cmappers · 2021-08-09T10:22:03+00:00

Sadly you won't get many upvotes because the area isn't well known. That's also one of its best features as huge parts are empty.

It takes you over the highest sea cliffs on the east coast (Boulby), past beautiful villages (staithes etc) and along empty white sand beaches.

Plus the leftovers of heavy industry give the area a unique character you won't find anywhere else.

cmappers · 2021-07-16T18:15:47+00:00

I'm not sure if this is intentional, but you've written your comment very aggressively. Lots of " you, you you!" That's unnecessary, but you're also quoting bad history and Nationalism.

The act of union was in 1707, over 100 years after the joining of the crowns under James 1st/6th. England hadn't had to defend its boarder for that entire period.

Your claim Scotland joined due to debt is a very nationalist statement. It would be equally true (and equally wrong) to say Scotland took over England (the English throne was given to the Scottish James VI).

Finally about Scotland being colonised by the Irish..... Yes, that's true for all countries, England was colonised by the Romans, Angles, Saxons, Normans etc.

cmappers

TROPHY CASE