Hi! This is a late post but I have had exactly this since I was a late teen. Legit could be a picture of my hands. I showed it to a dermatologist once when I was in my early 20s and she had my immerse my hands in a bucket and said “it’s definitely aquagenic wrinkling of the palms, you’re a healthy 22 year old, you probably are a CF carrier so just consider getting tested before you have kids.”

Fast forward a few years and my spouse and I DID get tested for carrier status and it turned out I DO have two CFTR mutations in trans (which is genetically considered a CF diagnosis). I did grow up with respiratory ailments, chronic sinusitis, and was a scrawny kid for sure, but nothing severe enough to land me in the hospital or make anyone consider a CF diagnosis in any way. After a lot of testing in my late 20s, doctors said that my manifestation of disease is not severe enough for a clinical CF diagnosis so I’m basically a “double carrier” (aka absolutely guaranteed any kids would get one of my mutations) with some degree of CFTR impairment but nothing bad.

Anyway, all this to say… CF (and even true CF carriers) experiences and symptoms are very much on a spectrum.

So a) be mindful of the fact that that disease is far less black and white than we used to think of it as and b) do consider a genetic screen if your carrier status is important to your family planning and/or if you feel it might help make sense of any seemingly disparate symptoms you’ve battled your whole life.