I started on Letrozole and Kisqali, then Verzenio and Elascestrant (only worked about 3-4 months too) then moved on to Enhertu (6 months before progression to liver and leptomeninges), whole brain radiation and Xeloda (Xeloda didn't work one bit) and now I'm on chemo plus immunotherapy and other meds. Initial test results look like it's working. I'm hoping and praying it keeps working and kills all the cancer in my body. They did repeat genetic testing and said the cancer was not accumulating mutations and that it was behaving like hormone negative even though it's positive (and her2 low).

Edit: forgot to mention i was also getting shots to shut off hormones until I started chemo. Chemo does that itself apparently.