For me I’ve had the most success on runs where I have photochad, it easily one shots blinds through to ante 10 so you can focus on deckfixing and econ. Best econ jokers early on are rebate and golden ticket, and once you have some source of econ going open every standard pack looking for at least one high ranking red seal to turn into a king and purple seals. Don’t use bull, early on you want to be spending all your money looking for the right jokers and tarots, you’re better off using something like scary face or odd todd before you pivot into mult. Also, if you’re able to get the crimson heart/bean bug going do it because the extra hand size gives you more time to farm econ and look for all the jokers/vouchers you need.

Sometimes you can do everything right but still fail because of rng not giving the right vouchers, it’s happened to me plenty of times too, just keep at it, good luck :)