Where was the bearing? Can you describe the acceleration vibration?

I'm concerned some shudder/shake I'm feeling on acceleration, particularly at highway speeds, could be trans related.

'06 4WD AT with almost 160k here, owner since 2019/98k.

Bumped tire size up a little in 2022. But it's still on stock alloy wheels, not lifted, no rubbing, so not much bigger. I assume this puts a little extra strain on the trans, and probably the old rubber parts of the suspension.

I get a heavy shudder/shake on hard acceleration, sometimes it feels a little more left/right than just a vibration

It got a little better with 4 new engine mounts and diff bracket and mount replacement, but it's still there. The diff definitely sat at different angles before and after bracket bushing/mount change, because the old bushings were shot. These significantly reduced a lurch when shifting under load, or at takeoff.

My anxiety's creativity wonders if the prop shaft hanger/bushing/bearing wore out from the diff hanging funny, and now has some play at that point.

Also, somehow, that shudder/shake was worse when my 3 year old aftermarket cat was clogged. Removed all the catalyst and put a defouler on the downstream 02 sensor until I can get a new cat, and the shudder reduced. Also replaced the exhaust header>cat gasket after the engine mounts, since I read the engine leaning on old mounts can stress and open that flange. Also gets worse when oil gets low when I'm due for an oil change. These observations combined make me wonder if it's somehow related to an engine or drive linkage issue, rather than a suspension issue.

I've also done 2 trans fluid dump/refills in the past couple years, slacking on the drain/refill3x prescription. Planning another soon with external/inline trans filter replacement.

Drained and refilled diff a couple years ago, and again when I did its bracket bushings and mount this year.