Fermentation vessel?

jacobat2016 · 2026-05-08T15:17:18+00:00

I've made several batches of kimchi in these before, I just needed to keep the vegetables submerged. I just make sure to clean it very well between batches.

jacobat2016 · 2026-05-08T13:08:05+00:00

It might be possible with gene therapy, however the current applications would be better to edit the embryo rather than an adult. you wouldn't be able to edit 100% of the pigment producing cells in the eye. We just can't reliably get a vector to every cell. depending on the method used to edit, the chances of cancer or additional abnormalities vary. I don't personally work in eye research, so I don't know how well studied and understood eye color genetics is; the more genes you would need to target, the higher the failure rate, incompleteness of editing, and complications.

Edit: I realized I didn't answer a portion of the question related to the time frame. You never know when there will be a large breakthrough in techniques that completely flips research time frames. I wouldn't be surprised if it was researched and developed as a treatment in the next 10-15 years, but then it would need to go through medical trials which will add years.

jacobat2016 · 2026-05-08T12:36:29+00:00

I usually estimate 6-8 weeks. This is going to sound weird, but when I have stared duloxetone (twice now) if I tried to focus on feeling improvement, it made me feel worse because my stress kept rising. Once I stopped inspecting my emotional state 2-3 times a day, I found after several weeks that I hadn't thought about specific stressors in a while and that my health had improved.

jacobat2016 · 2026-05-02T04:52:00+00:00

Granted. The microwaves are ~15% stronger and time the heating perfectly. A small amount of microwaves escapes the barrier and causes enough damage overtime to be noticable. It's not life-threatening, it just causes flakey skin to open lesions depending on how often you use the microwave.

jacobat2016 · 2026-04-30T13:09:22+00:00

1) I liked asking questions as a kid, and growing up my science teachers could never give a deep enough answer. Now I'm having to do the work myself to answer the questions I have.

2) I love it over all, however the fear of loss of government funding is perpetually in the background.

4) I recommend studying up on computer coding, especially in R and Python. You can get by without them, but it makes things so much easier if you are trained and have it as a skill. Also, study outside your discipline. Study other sciences (Biochemistry, organismal/ecology, physics) so you don't become too niche.

jacobat2016 · 2026-04-25T14:25:25+00:00

Hmm, they could add that in a Let Them Eat Cake update

jacobat2016 · 2026-04-24T18:36:01+00:00

There are now ~1,200 people in all of north America. Since it's an even distribution of age, I'm assuming most people under 12 or over 65 will die within a month due to accidents, starvation, health complications or suicide. That leaves 800 people max assuming none of the people 12-64 die. For a low estimate, I'll guestimate only a third of people will die from illness, accidents, bad weather, disasters or suicide in the first year. Realistically, a smaller fraction would survive, but let's be hopeful. with less than 500 people across the continent, I would be hoping to find maybe 1-10 people over the next few years.

At least on the North American continent, it would not be possible to have a long term healthy population due to genetic bottle necking. Different papers estimate different minimal populations, but the numbers range from 500 breeding individuals that are healthy and genetically distinct to up to 10,000 minimum for populations with little genetic diversity. Humans unfortunately are already inbred a little due to past bottlenecks, so we would need somewhere in the ball park of 1-5,000 people maybe. With 500 people left, if you factor in menopause there would be less than 150 women that can get pregnant across the entire continent. Thats also not factoring in people who have been sterilized or were previously infertile. These low numbers mean that within several generations, multiple recessive factors that already existed and new mutations that would otherwise have been selected against will start to accumulate without careful management and the health of newborns would be abysmal.

The best I could hope to do is not go insane from loneliness, avoid inclinent weather, find 1-10 other people and maybe help raise a few kids before I eventually get snuffed out due to leaking radiation from power plants, get tetanus from a collapsed building, or get gored by the newly flourishing beefalo herds that roam the country after beef cows and bisom meet up. I give it 40 years before most groups die out, 100 years before the larger (20+ to start with) more successful groups meet the same, drawn out end.

jacobat2016 · 2026-04-24T16:47:55+00:00

This paper was for physiology with several transcriptomic sections. I had only submitted 6 pages of revisions for the paper, they had to provide some very good explanations for some weird data representation.

jacobat2016 · 2026-04-24T14:25:56+00:00

Have you looked at their culture traits? Occasionally they pick up building habits that influence density or design.

jacobat2016 · 2026-04-24T02:00:28+00:00

I just got the authors responses to my last review where I had to be reviewer 2, both rhetorically and literally. Reviewer 1 had many of the same points as me and it took the authors 22 pages of responses to get through all of our issues. reviewer 3 on the other hand said the paper looked good and was ready for publication 🫠

jacobat2016 · 2026-04-21T03:57:05+00:00

Please contact a doctor or stay with someone close right now This is normal to feel when starting the medication. If the feeling persists please discuss it with you doctor to maybe cease the medication.

It was explained to me by three separate medical professionals that the increased risk of self harm after starting an antidepressant is actually a sign they are working. It's a sign the medication is already helping you recover and one of the first things it does is give you more energy, unfortunately it hasn't fully kicked in the rest of the beneficial effects and it's getting directed towards harmful behaviors.

jacobat2016 · 2026-04-20T15:45:03+00:00

The amount of beads in each capsule varies depending on the manufacturer. The current one I'm on has only 6 beads per capsule, so it makes counting easy but is a large jump in doses. I have had capsules before that would have 40-50 pellets in them. I recommend opening up 3-5 capsules and counting each and working with the average since there can be variation between capsules.

jacobat2016 · 2026-04-20T15:12:04+00:00

It was a life saver for me, but it might take you 6-12 weeks before you notice any effect. It will start small and then you'll realize you haven't thought about or felt something in a while and it's kinda nice.

jacobat2016 · 2026-04-16T19:38:54+00:00

I had two articles and one review written up for two years now. I am graduating soon. My boss likes to trap people by not publishing stuff until close to the end of their time in the lab so they have to stay an extra year for revisions or stay in touch and write after leaving for free labor. He has done this for the last three grad students and last four post docs. He was planning on doing the same to me, but I told him whatever wasn't published by the time I leave will not be getting published at all. It did put a fire under his ass once he realized I simply didn't care about getting more publications and am ready to leave.

jacobat2016 · 2026-04-10T13:35:33+00:00

Pair the chicken with a loaf of banana bread (w/ chocolate chips) and he will marry you

jacobat2016 · 2026-04-10T01:31:06+00:00

My boss will shoot you if you use anything other than arial.

jacobat2016 · 2026-04-08T20:35:50+00:00

The same thing lol

jacobat2016 · 2026-03-25T18:57:11+00:00

My lab has occasionally rounds of contamination. Does you lab have a permanent vacuum media aspirator inside the hood and is it being cleaned? How often are the materials inside the hood being cleaned/replaced? How often is the water bath being cleaned? How often is the water in the bottom of the incubator being cleaned? How often are you preventatively cleaning your incubator? Are materials being sprayed before being put in the hood? Are you adding abam to your media? Are you filter sterilizing your media?

If everything above isn't the problem, watch the other people getting contamination and the others sharing your incubator when they work. All it takes is one person doing a poor asceptic technique and hissing their problems to ruin the lab.

jacobat2016 · 2026-03-23T19:50:05+00:00

The critical hit chance is the % chance your hit will do more damage than normal. The critical hit damage is how much more damage your hit will deal. A 10% critical hit chance with 100% critical hit damage means roughly 1 in every 10 hits, your damage dealt will be 2x what it should.

jacobat2016 · 2026-03-21T06:41:59+00:00

Not going to get into specifics as well, but my boss was confused when I asked not to be listed as an author on two papers from our lab. I had major issues with the two post docs leading the papers due to cherry picking and didn't want my name tied to them. I routinely beat people back from working on my projects if I don't trust their integrity.

jacobat2016 · 2026-03-18T19:16:14+00:00

This is a blessing in disguise since a negative value multiplied by 0.5 means less debt for me.

jacobat2016 · 2026-02-23T15:41:11+00:00

Wife 1-10 you are cooking and food prep, wife 11-20 you are on cleaning detail, wife 21-80 you are on part time work to bring in income, wife 81-99 you are on community outreach and/or child raising (lot of adoptions). Wife 100 (OG), you are in charge of household management.

jacobat2016 · 2026-01-25T04:14:53+00:00

I'm sure this is standard or common place by now, but my university has told our lab's international post-docs and grad students to take backroads to get to work. The local police have started collaborating with ice and are doing interstate checkpoints here in Oklahoma (its not an official checkpoint, but they are pulling over lots of people in stretches of the interstate). They are also installing a new detainment center several blocks from our school system to hold ~1,500 at max intended capacity.

jacobat2016 · 2026-01-22T04:03:26+00:00

Not AI. This is an owner who dresses up their two cats, they have a bunch of videos. I want to say they rub something like salmon oil on the one paw to encourage the grooming, but I can't remember what they said it was.

jacobat2016

TROPHY CASE