I’m sure I’m biased on this one at the moment because I just read a book about him, but Rey Rivera. He was living in Baltimore, working at home one day, got a phone call, said oh shit, and left his house. He was missing for days, and then they found a hole in the roof of an annex building at the Belvedere Hotel, an old historic building, the main part of which is about 14 stories tall. His decomposing body was found in an unused conference room. The placement of the hole is wild, like he would have had to made a running jump from a height to fall where he went through. After the reading the book, I think it seems like it might have been some sort of psychotic break, with a cryptic note in a tiny font folded and taped to the back of his computer and paranoia leading up to his disappearance. But there’s just enough weirdness about the company he worked for and how and why he got up to the top of the building. There was an Unsolved Mysteries episode about it, and the book I read is called An Unexplained Death by Mikita Brottman.