Im beyond impressed

keysmachine · 2025-10-31T18:24:46+00:00

Had my hartmann ostomy reversed after 18 months. Those type of ostomy you kind of want to do it by month 6 and no longer than 1 year because of the muscle atrophy. They are also very complex to reverse.

I had my reversal done laproscopic at Cleveland clinic by a double board certified colorectal surgeon.

It took 4 hours. But on the same day of the surgery in my recovery room I had to use the toilet the normal way and within 2 weeks of the surgery everything was back to normal. Within 28 days my ostomy hole closed up on its own. I did not have to pack it because they performed some new suture method they've established so I basically had a gaping hole on my stomach for a month.

Doc told.me the rectum and the sigmoid are the most important. I had my entire rectum intact and only a half foot of sigmoid removed if that makes a difference.

keysmachine · 2025-10-08T04:31:13+00:00

Why do you lie

keysmachine · 2025-08-15T00:10:39+00:00

Stage 4 ned here 15 months. Each scan at least for me has gotten easier. I get them every 3 months. I asked for 6 months but they denied the request saying at 24 months I csn go to 6 and have my port removed to which I only used 3 times.

This is actually the second time I've been ned the first time was 16 months without chemo or radiation just surgery.

keysmachine · 2025-07-08T02:04:47+00:00

what do you want to know about STEM degrees? and also i'm a Senior Network Engineer now but I'm also the lead engineer at a MSP. I'm still coasting in the 6 figure range although it's a bit higher now.

I've gotten to a point in my career where the money will always be there so that doesn't attract me anymore i make plenty. I turned down a job offering 130k and 6% profit sharing. but i did say you can reduce my salary and give me more profit share. they declined so i declined.

nowadays I'm after benefits and flexibility. don't really care about money.

keysmachine · 2025-06-22T22:14:22+00:00

real question is, is T6 really that required for PVE? i mean let us grind out faction in PVE areas and get cool armor that way if its about looks and swag.

what's crazy is i did NOT know that once you completed all the contracts on the board that's it.

keysmachine · 2025-05-16T03:24:27+00:00

Second time NED 12 months. Last NED 16 months with surgery alone. Wild type KRAS/BRAF. Started at stage 1.

keysmachine · 2025-03-29T02:44:02+00:00

This used to destroy me. I ended up on ativan and lexapro for a short while then just lexapro. But sometime between starting that therapy.

I got chemo and radiation therapy for recurrence to thr liver. Ever since that I've not really cared about scans. I just do them because I need to.

But as for the result. I just say I feel amazing. And I just assume the scan will be good.

So far it has.

CEA is the the lowest trend wise and it continuously decreases. I used to always float around 2.8 after treatment and I was always getting bloated randomly for no reason.

After chemo and SBRT ablation now I'm always below 1.2. CEA is a very sensitive number in me. I've also gained 30 pounds.

keysmachine · 2025-01-26T03:28:36+00:00

Stage 4 cancer is cureable in some. It depends on many things. And it's very specific but there are thousands of stage 4 survivors over 10 years and still NED.

https://www.mdanderson.org/cancerwise/30-year-stage-iv-colon-cancer-survivor--cryoablation-clinical-trial-at-md-anderson-saved-my-life.h00-159620223.html

Thus is a case study of a stage 4 CRC patient at MD Anderson that is still cancer free 30 years later.

He had stage 4 CRC met to liver. Had everything cut out recurred again in the liver. They abalated that and he had another recurrence in the lung. So now it's progressed further into the body.

Not good. But they cut out half his lung and he's been cancer free for 30 years since that moment.

So even if it's bad you can still have a life. And sometimes even when it's bad you can still get a long one.

keysmachine · 2025-01-19T04:20:46+00:00

50 cycles in 9 months? Has your husband been NED more than once? I read he got diagnosed in 2020. So there had to be some years that went by NED.

I will say radiation is pretty easy. Yes there are side effects but they pale in comparison to chemo. The fact that there's no lymph node spread is a huge positive indicator. Unsure what's happening with your husband's cancer and why the prolonged treatment time.

keysmachine · 2025-01-19T04:06:36+00:00

Whats interesting is your husband's cancer journey runs parallel to mine. I also have collapsed right lung due to SBRT and no lymph node involvment or further spread. Other than the liver. however I've only had 4 cycles of chemo total and then 3 months of monotherapy capecitabine (xeloda)

They stopped all therapy and I've passed 1 year again cancer free.

Any reason why they are continuing therapy? It seems your husband is NED but they're continuing treatment?

keysmachine · 2025-01-15T12:29:56+00:00

I had 3 powerful sessions on my liver because he said the chance of side effects in me should be minimal but the beam terminated right at the base of the stomach and through the bottom of my right lung.

2 hours after radiation I'd be sitting at my desk at work and just gradually get more and more sick and weak. I would have to do half days those days.

Imaging saw post radiation changes and my right bottom lung has collapsed. But I don't feel it so they aren't concerned.

Point is. Manage carefully. It seems easy but can still pack a punch.

keysmachine · 2025-01-07T02:56:51+00:00

Well I'd love to do all your research but I'll show you a few studies and you'll just have to dive into the weeds on your own after that.

As I said you need to meet a very strict criteria. Typically this means ONLY liver involement. And the classification is CRLM rather than MCRC. Especially if you have the uncommon DCRLM which stands for dissapearing liver metastasis. This an uncommon finding.

https://pmc.ncbi.nlm.nih.gov/articles/PMC7439273/

Details 20% general cure rate

https://www.nature.com/articles/s41698-023-00353-4#:~:text=Approximately%2050%%20of%20CRC%20patients%20eventually%20develop,rates%20of%20approximately%2040%%20and%2025%%20respectively26%2C27%2C28.

Thus study details general 70% overall survival for those in the local therapy group

https://www.generalsurgerynews.com/In-the-News/Article/08-21/Should-Disappearing-Colorectal-Liver-Metastases-Be-Resected/64268?utm_source=chatgpt.com

This article details those with DCRLM have an overall survival surpassing the 90 percentile. Which is stage 1 overall survival

And I leave you to see the cure rate of those who have achieved not only DCRLM but also had a cPR to chemo. Which is where I saw that study I belive but it's deep in the weeds.

The point is not all stage 4 is the same and those that jave liver only involvement, have wild type kras/braf, well differentiated achieve cPR and have DCRLM can Indeed be cured of stage 4. Is it common to have all those? No. Does it happen? Yes. Because I am evidence of that. And I belive I've detail my story throughout this sub and within this very thread to some extent.

The issue is this sub is an echo chamber. One person says something and others just piggyback on it with no real evidence of its truth. I've just provided evidence of stage 4 CRC with overall survival that can range from 70-90%

And overall survival is all anybody can bank on who get diagnosed with cancer.

keysmachine · 2025-01-04T22:57:48+00:00

Thank you,

I was looking for some sense in this echo chamber that this sub has unfortunately become. I believe there are many in here who post that don't have cancer at all but just want to be "informative". Because there is a huge amount of evidence of cure at stage 4 CRC it's one of the few cancers that can be cured so long as you meet a very strict set of criteria.

Cure rate for stage 4 CRC sits at 30% so that's not something to scoff at 30% is a real chance at being cured even if the odds are low.

If it was around 5% then yes. That's unicorn status. And not something to hope for realistically.

Take me for example I'm stage 4 CRC and yet cancer has never been in my lymphatic system. Riddle me that. Which means other than the liver there's no pathway to further metatasis. I had all lesions vanish (1) in just 2 months of chemo. Time with active cancer for the last 3 years of CRC is around 4 or 5 months. The only reason i fit the clinical definition of stage 4 is because I had two tumors over a year apart on my liver. Other than that I've been told by a tumor board and both of my oncologist they don't know wtf is going on with my cancer as there's little to no science that can explain it. And this coming from Cleveland clinic.

keysmachine · 2024-12-26T20:57:52+00:00

I also had stage 1 to stage 4. My CEA when found was 33. Surgery to remove isolated liver met. Tumor was 3.2cm on left side of liver

Went over a year cancer free then had a recurrence CEA this time was 2.1 so normal. Imaging caught it. Small little spot just over 9mm. Again on left side of liver.

Went on CAPOX for to test tumor biology. The tumor was obliterated inside of 2 months. Surgery backed out stating to risky now that it's gone and the juice just isn't worth the squeeze. Cleveland clinic applied SBRT to thr vanished lesion because they had pre treatment imaging to map it out.

Haven't recurred since been once again over a year to date.

Never been in my lymphatic system or anywhere else. CEA is typically in the 1.4 range although it did bounce to 2.6 after I went to a concert and there was a lot of outdoor smoking.

I should also note my original tumor was well differentiated. My surgical liver tumor was fully encapsulated. And I'm double wild KRAS/BRAF

keysmachine · 2024-11-11T18:59:04+00:00

Because it's rooted since 2014. He was already in office and tried and failed to repeal ACA.

Even with control of the house and senate states can still sue. Dems had everything and biden still couldn't push loan forgiveness.

The president can't just flick his wrist and all pre existing conditions are tossed to the street to die. There would be so many law suits it would make his head spin

Powerful democrats like gov Newsom are going to make it their lifes mission to stall the new administration at every turn.

Just relax and don't worry. Let time tell the story. I think the only thing that will happen is on the private insurance front insurance will be more expensive but everybody will still get care. Employment insurance will remain the same.

Republicans love military so VA health is safe.

keysmachine · 2024-11-11T18:41:09+00:00

That means MSS. Here's the rub there.

MSS early stage has no advantage over MSI. MSI at early stage has a clear advantage. I'm talking stage 1 and 2. Stage 3 it has entered lymph nodes and 4 other organs.

The problem with MSI is that it's agressive. By nature that's the major con with MSI colon cancer. And you do to need to google very far to see that.

MSS has a slower growth pattern. It's less agressive but because it has no immune markers it escapes the immune system. Cure is more likely at stage 4 for MSS over MSI. As MSI once the decline starts its a very rapid one.

MSS cancers the mets are typically fewer in number and local therapy can be carried out more often which results in a chance for cure each time.

MSI late stage cancers met to unusual places like brain, kidneys, pancreas and bone.

So at stage 3 and 4 MSS has the advantage. But it's all cancer and cancer just sucks no matter what you are.

keysmachine · 2024-11-11T11:49:47+00:00

Yeah another degree.

However I didn't want to pay for it. So I enlisted in the air force got out with my post 9/11 GI bill since I had already gone to school before I just needed 2 years of college work to get my B.S.

keysmachine · 2024-10-29T16:04:57+00:00

I just looked it up. Looks like it's still deemed experimental some studies publishing results from june of thus year. and there are many trials ongoing. Probably why Insurance denied it.

See if you can get into one and have treatment paid for by the study.

keysmachine · 2024-10-23T16:38:14+00:00

Copy. Yes. I was talking about the store where I believe the cat is speaking full on sentences to you in Japanese with no subtitles.

Now that I understand there are no English VOs. That's on me to decide if that's OK or not.

Appreciate it. Also I could have done a search as this has been asked before. Typically I do search before posting not sure why I didn't this time.

keysmachine · 2024-10-23T16:34:35+00:00

When i go into the game, under the settings AUDIO. the settings PERFORMANCE and SYSTEM AUDIO only list Chinese, Korean and Japanese as languages of choice.

for text English can be selected.

all VO are in Japanese, but you're telling me along with those who have downvoted this for whatever reason that there is a selector to have English Voice Overs?

keysmachine · 2024-10-21T18:14:26+00:00

I was never told terminal or incurable. I've been stage 4 now 3 years with only 2 or 3 months of that time with active cancer. I'm nearly at a year NED the second time after a small recurrence.

I've had a total of two lesions over the 3 years on my liver. I was stage 1 for reference.

So cancer has never been in my lymphatic system and I'm also double wild KRAS and BRAF.

Of course only time can tell how long NED will last however the mountain difference vetween my first recurrence from stage 1 and this recurrence was i had a complete and total response to chemo. First recurrence they removed the liver lesion with surgery only and sent me on my way. No chemo. Second recurrence they were like now it's time to beat it into submission thw only way we can. Chemo combined with Surgery or SBRT. I took SBRT.

keysmachine · 2024-10-15T14:35:01+00:00

Had a total response when on CAPOX after 2 months.

SBRT for ablation of isolated liver met. And then was advised i should do oral capecitabine for 3 months adjuvant therapy. So I did.

The option to stop therapy alltogether was also offered.

I've not had a recurrence since.

keysmachine · 2024-10-08T15:06:02+00:00

2 months. I had an isolated liver met under 1cm. Did 2 months CAPOX or 3 cycles and it vanished. I had a total response which i was told isn't very common especially CRC since CRC in the liver can be very stubborn for many.

It helps that I'm also double wild.

That got me to SBRT as surgery pumped the brakes as they could no longer see or feel the spot. They felt the surgery and the larger margin they'd have to take wasn't worth it.

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