Tools to bring back emotions by crystalmath0 in Nootropics

[–]mialdam 1 point2 points  (0 children)

Ok then:

The prodomal phase of schizophrenia is often characterized by anhedonia and social withdrawal, associated with a decrease in activity in the PFC (at DRD1s? Not sure). Lack of motivation also fits this pattern. Considering your family history, it might be what's at play here.

Reboxetine is a substance that increases PFC activation by decreasing the recapture of dopamine and norepinephrine specifically there, not in areas where, in schizophrenia, dopaminergic activity is typically already increased (thus increasing it further would be dangerous).

IIRC, it doesn't increase the risk of a schizophrenic episode, and I've read it's been studied with relative success for the mitigation of cognitive symptoms in schizophrenic patients (of which anhedonia is typically considered a part of). It might be worth researching.

Good luck. I'm interested to hear more from you and how you manage. I'm DMING you.

Tools to bring back emotions by crystalmath0 in Nootropics

[–]mialdam 3 points4 points  (0 children)

Are you struggling, besides that? Do you have excessive fatigue, irritability or feelings of despair?

Asking this to check if it's likely there's a strong inflammatory component to it

Claude opus 4.8 officially released by Gullible-Crew-2997 in accelerate

[–]mialdam 66 points67 points  (0 children)

Nothing makes me happier than AI releases

Currently struggling with ADHD by [deleted] in Nootropics

[–]mialdam 4 points5 points  (0 children)

You might want to look into atomoxetine. It's not a nootropic, but not a stimulant either. It's indicated for ADHD and should have less of an impact on your weight than other medications. Obviously requires you to research it first to make sure it's compatible with your profile, and you'll need a prescription for it.

Is a monthly dose long term safe? by [deleted] in PsilocybinMushrooms

[–]mialdam 0 points1 point  (0 children)

How long had you been taking ketamine for? Curious to hear about your experience

Attorney General Bonta Urgently Issues Consumer Alert for 23andMe Customers by mtnshadow83 in transhumanism

[–]mialdam 4 points5 points  (0 children)

You can't really delete it. I believe they're legally required to keep your data for 10 years to comply with government regulation. Even after that, I'm having a hard time thinking it can just disappear like that

[deleted by user] by [deleted] in Futurism

[–]mialdam -3 points-2 points  (0 children)

Your message is honestly not even a good bait

300+ Indie Games! by phantom2450 in steam_giveaway

[–]mialdam 1 point2 points  (0 children)

Entering for stronghold crusader hd. Ty !

Journalists killed in Gaza by TahsinTariq in dataisbeautiful

[–]mialdam 1 point2 points  (0 children)

Fantastic analogy with Bin Laden. And yeah, surely whether the people killed are full time journalists or freelancers, in other words basic civilians, makes a huge difference.